ArticleJournal of anatomy2026
3D transparent technology displays the developmental patterns of ductus arteriosus morphology in chicken embryos before and after birth.
Article in Journal of anatomy, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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1 citing paper in PubMed.
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Authors and funding
8 authors.
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Abstract
The ductus arteriosus (DA) is a critical fetal vascular structure that shunts blood from the pulmonary artery to the aorta, bypassing the non-functional fetal lungs. Postnatally, it undergoes active remodeling and closure, forming the ligamentum arteriosum. Abnormal persistence (patent DA, PDA) can lead to significant health issues. Chicken embryos, with their rapid development and accessibility, serve as a valuable model for studying DA morphogenesis. This study explores how 3D transparent technologies have advanced our understanding of DA development in chicken embryos, emphasizing pre- and post-hatching morphological changes. We use glycerol transparency technology to show the DA development processes with 3D stereo effect and the H.E technology to show variation of the horizontal sections of DA. Chicken models provide insights into PDA pathophysiology, aiding drug testing (e.g., caffeine exposure). 3D imaging could validate therapeutic efficacy in vivo, bridging preclinical and clinical research.
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