Evidence map›Paper›PMID 41792868›Full record

ArticlePlant biotechnology journal2026

ZmWRKY29 Transcriptionally Represses ZmRBOHC to Attenuate ROS Production and Facilitates Gibberella Stalk Rot Susceptibility in Maize.

Jingye Fu, Li Zhu, Luyao Wang, Wenzheng Pei, Chenying Zhu, Fukun Bao, Yuhan Zhang, Gang Chen, Qiang Wang

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Plant biotechnology journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jingye FuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID https://orcid.org/0000-0002-0378-2138
Li ZhuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, Sichuan, China.
Luyao WangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, Sichuan, China.
Wenzheng PeiState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, Sichuan, China.
Chenying ZhuState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, Sichuan, China.
Fukun BaoState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, Sichuan, China.
Yuhan ZhangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, Sichuan, China.
Gang ChenCrop Research Institute, Shandong Academy of Agricultural Sciences, Jinan, Shandong, China.
Qiang WangState Key Laboratory of Crop Gene Exploration and Utilization in Southwest China, College of Agronomy, Sichuan Agricultural University, Chengdu, Sichuan, China.ORCID https://orcid.org/0000-0002-7051-8177

Funding

National Natural Science Foundation of China 32001446Natural Science Foundation of Sichuan Province 2024NSFSC0332
6 · The paper itself

Abstract

Gibberella stalk rot (GSR), caused by the fungal pathogen Fusarium graminearum, severely threatens maize production. However, the molecular mechanisms underlying maize resistance to GSR remain poorly understood. Here, we have identified ZmWRKY29 as a transcriptional repressor induced by F. graminearum infection, which negatively regulates maize resistance to GSR. Overexpression of ZmWRKY29 significantly compromised GSR resistance with a marked reduction in reactive oxygen species (ROS) production and callose deposition, while its mutation enhanced resistance and elevated ROS accumulation. RNA-seq revealed that the expression levels of two respiratory burst oxidase homologues, ZmRBOHA and ZmRBOHC, were decreased in ZmWRKY29-OE lines following F. graminearum challenge. ZmWRKY29 directly binds to the W-boxes in the promoters of ZmRBOHA and ZmRBOHC to repress their transcription. Moreover, mutation of ZmRBOHC similarly led to increased susceptibility and diminished ROS accumulation, confirming that ZmWRKY29-targeted ZmRBOHC is required for ROS production and GSR resistance. Thus, ZmWRKY29 acts as a susceptibility factor, repressing GSR resistance possibly by inhibiting ZmRBOHC-mediated ROS production. This highlights a pathogen strategy of exploiting host transcriptional machinery to suppress ROS defences and facilitate infection.

Indexed as

GibberellaPlant DiseasesPlant ProteinsReactive Oxygen SpeciesZea maysDisease ResistanceFusariumGene Expression Regulation, PlantPromoter Regions, GeneticTranscription FactorsPlant ProteinsReactive Oxygen SpeciesTranscription FactorsGibberella stalk rotROSsusceptibilityZmRBOHCZmWRKY29

Identifiers

PMID41792868
PMCPMC13205747

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.