Evidence map›Paper›PMID 41792614›Full record

ArticleBMC microbiology2026

Clostridium zhoujianii sp. nov., a novel gram-negative species isolated from bat feces and its genetic characteristics.

Jian Zhou, Tao Gu, Jingzhu Zhou, Xiaoxiao Zeng, Ying Liu, Fengming Chen, Yong Hu, Shijun Li

Abstract read
In one paragraph

Article in BMC microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jian ZhouKey Laboratory of Microbio and Infectious Disease Prevention and Control in Guizhou Province, Guizhou Center for Disease Control and Prevention, Guiyang, 550004, China.
Tao GuSchool of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, 550025, China.
Jingzhu ZhouKey Laboratory of Microbio and Infectious Disease Prevention and Control in Guizhou Province, Guizhou Center for Disease Control and Prevention, Guiyang, 550004, China.
Xiaoxiao ZengKey Laboratory of Microbio and Infectious Disease Prevention and Control in Guizhou Province, Guizhou Center for Disease Control and Prevention, Guiyang, 550004, China.
Ying LiuKey Laboratory of Microbio and Infectious Disease Prevention and Control in Guizhou Province, Guizhou Center for Disease Control and Prevention, Guiyang, 550004, China.
Fengming ChenKey Laboratory of Microbio and Infectious Disease Prevention and Control in Guizhou Province, Guizhou Center for Disease Control and Prevention, Guiyang, 550004, China.
Yong HuSchool of Public Health, the Key Laboratory of Environmental Pollution Monitoring and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, 550025, China.
Shijun LiKey Laboratory of Microbio and Infectious Disease Prevention and Control in Guizhou Province, Guizhou Center for Disease Control and Prevention, Guiyang, 550004, China. zjumedjun@163.com.

Funding

Key Laboratory of Microbiol and Infectious Disease prevention &Control in Guizhou Province Qiankehe Platform Talent-ZDSYS [2023] 004Project for Public Health Talent Cultivation of China Guo Jikong Zong Ren Han [2024] 122The local science foundation of Guizhou Province guided by the Central Committee of China Qiankehe [2025] 024
6 · The paper itself

Abstract

A strictly anaerobic, rod-shaped bacterial strain, designated LP20ᵀ, was isolated from the intestinal contents of bats collected in Qiandongnan, China. Phylogenetic analysis of the 16 S rRNA gene revealed that strain LP20ᵀ shared its highest similarity with Clostridium paraputrificum ATCC 25780ᵀ (98.10%), a value below the accepted threshold for species delineation. Whole-genome sequencing further supported its taxonomic novelty, with ANI, dDDH, and AAI values to the closest relatives all falling well below species-level cutoffs. Strain LP20ᵀ exhibited unusual Gram-stain-negative morphology, grew optimally at 30–37℃ and pH 7.0–8.0, and possessed distinctive fatty acid and polar lipid profiles, including the presence of an unidentified aminophospholipid. Phenotypic assays revealed several metabolic and enzymatic traits that differentiated LP20ᵀ from its closest phylogenetic neighbors. 16 S rRNA amplicon sequencing and metagenomic screening confirmed the presence of this species in multiple bat hosts, suggesting a wider distribution within bat gut microbiomes. Functional genomic analysis indicated enrichment of genes involved in carbohydrate metabolism and a limited antibiotic resistance profile. Based on polyphasic evidence, strain LP20ᵀ represents a novel species within the genus Clostridium, for which the name Clostridium zhoujianii sp. nov. is proposed. The type strain is LP20ᵀ (= JCM 37970ᵀ = GDMCC 1.5627ᵀ).

Indexed as

ChiropteraClostridiumFecesAnimalsBacterial Typing TechniquesBase CompositionChinaDNA, BacterialFatty AcidsGenome, BacterialPhylogenyRNA, Ribosomal, 16SSequence Analysis, DNAWhole Genome SequencingDNA, BacterialFatty AcidsRNA, Ribosomal, 16SBatClostridium sp. nov.Genomic functionPolyphasic taxonomyZoonotic potential

Identifiers

PMID41792614
PMCPMC13081657

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.