ArticleScientific reports2026
LLM-based medical dialogue dataset generation with automated instructions.
Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Constructing medical dialogue datasets poses significant challenges owing to legal and privacy concerns. In the wake of the advancement of large language models (LLMs), automated instruction generation grounded in LLMs has emerged as a promising approach for dataset construction. However, the existing methods often overlook the integration of domain knowledge, such as the standards and regulations stipulated in official documents. This renders the generated instructions and corpus of reduced value. In this work, we propose a new LLM-based automated instruction generation framework to build a medical dialogue dataset compliant with the guidelines of Medical Chinese Test (MCT). The framework involves the construction of a hand-crafted instruction set, corpus refinement, instruction sampling using maximum marginal relevance, and the K-means algorithm. By incorporating domain-specific knowledge and adopting instruction sampling strategy, the generated instructions and corpus basically meet the MCT standards. We tested this generation framework in the experiment with ChatGPT (gpt-3.5-turbo) and the medical LLM model Zuoyi, finding that compared to real-world medical dialogue datasets, the generated dataset MCT-Chat consisting of 20k examples demonstrates excellent performance in terms of both objective and subjective indicators.
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