Evidence map›Paper›PMID 41791852›Full record

ArticleThe journal of obstetrics and gynaecology research2026

Reirradiation for Recurrent Cervical Cancer Within the Previous Radiation Field Using a Bioabsorbable Spacer: A Case Report.

Yusuke Matoba, Yuriko Oomori, Ikuno Nishibuchi, Shinnosuke Uegami, Kosuke Nakamoto, Takuto Uyama, Katsuyuki Tomono, Suguru Nosaka, Hiroki Ohge, Shinya Takahashi and 3 more

Abstract readCase Reports
In one paragraph

Article in The journal of obstetrics and gynaecology research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Yusuke MatobaDepartment of Obstetrics and Gynecology, Hiroshima University Hospital, Hiroshima, Japan.ORCID https://orcid.org/0000-0002-2609-1778
Yuriko OomoriDepartment of Obstetrics and Gynecology, Hiroshima University Hospital, Hiroshima, Japan.
Ikuno NishibuchiDepartment of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Shinnosuke UegamiDepartment of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Kosuke NakamotoDepartment of Obstetrics and Gynecology, Hiroshima University Hospital, Hiroshima, Japan.
Takuto UyamaDepartment of Obstetrics and Gynecology, Hiroshima University Hospital, Hiroshima, Japan.
Katsuyuki TomonoDepartment of Obstetrics and Gynecology, Hiroshima University Hospital, Hiroshima, Japan.
Suguru NosakaDepartment of Obstetrics and Gynecology, Hiroshima University Hospital, Hiroshima, Japan.
Hiroki OhgeDepartment of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Shinya TakahashiDepartment of Surgery, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Yuji MurakamiDepartment of Radiation Oncology, Graduate School of Biomedical and Health Sciences, Hiroshima University, Hiroshima, Japan.
Ken YamaguchiDepartment of Obstetrics and Gynecology, Graduate School of Biomedical Sciences, Hiroshima University, Hiroshima, Japan.
Kouji BannoCenter of Maternal-Fetal/Neonatal Medicine, Hiroshima University Hospital, Hiroshima, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Reirradiation for cervical cancer recurrence in previously irradiated fields is challenging due to dose limitations. To our knowledge, this is the first case report describing successful reirradiation using a bioabsorbable spacer for vaginal cuff recurrence after initial concurrent chemoradiotherapy (CCRT) and hysterectomy. A 70-year-old woman with cervical cancer Stage IIIC2r initially received CCRT and chemotherapy. Three years later, uterine recurrence led to hysterectomy. Eighteen months post-surgery, vaginal cuff recurrence was diagnosed by imaging and tumor biopsy. A bioabsorbable spacer was surgically placed around the vaginal cuff tumor via an open abdominal approach. Reirradiation (55 Gy in 22 fractions) was started 23 days postoperatively. Use of the spacer provided adequate dose reduction to the small bowel, sigmoid colon, and rectum, with the rectal D1cc reduced to 37.9 Gy. Mild paralytic ileus occurred, but resolved conservatively, and there were no severe complications. The patient remains disease-free at 6 months post-treatment. In this case, bioabsorbable spacer placement allowed safe reirradiation for cervical cancer vaginal cuff recurrence. This technique may represent a promising approach for selected patients with in-field recurrent cervical cancer, although further accumulation of cases and longer follow-up are required.

Indexed as

Absorbable ImplantsNeoplasm Recurrence, LocalRe-IrradiationUterine Cervical NeoplasmsAgedFemaleHumansbioabsorbable spacercervical cancerradiotherapyrecurrencereirradiation

Identifiers

PMID41791852
PMCPMC12965828

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.