Evidence map›Paper›PMID 41790933›Full record

ArticleScience immunology2026

Identification and characterization of dietary antigens in oral tolerance.

Jamie E Blum, Ryan Kong, E A Schulman, Francis M Chen, Rabi Upadhyay, Gabriela Romero-Meza, Dan R Littman, Michael A Fischbach, Kazuki Nagashima, Elizabeth S Sattely

Abstract read
In one paragraph

Article in Science immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Intestinal uptake regulates T cell responses to dietary antigens.bioRxiv : the preprint server for biology · 2026
    Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. bioRxiv : the preprint server for biology · 2025
    Article
  10. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Jamie E BlumDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-2168-5390
Ryan KongDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0001-8280-8967
E A SchulmanHoward Hughes Medical Institute, Stanford University, Stanford, CA 94305, USA.
Francis M ChenDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-6615-4155
Rabi UpadhyayDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-2154-0132
Gabriela Romero-MezaDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0009-0003-0984-3370
Dan R LittmanDepartment of Cell Biology, New York University School of Medicine, New York, NY 10016, USA.ORCID 0000-0002-2850-8688
Michael A FischbachDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0003-3079-8247
Kazuki NagashimaDepartment of Bioengineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-8593-136X
Elizabeth S SattelyDepartment of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.ORCID 0000-0002-7352-859X

Funding

Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Richard Lewis Possemato · 1985 to 2026
$83.1M
cGMP Manufacture, Fill-Finish, Release, Analytical and Stability Testing and Stability Program of a Nanoparticle Based HIV Envelope Vaccine75N93022D00005 · NIAID · INTERNATIONAL AIDS VACCINE INITIATIVE · PI HASSELL, THOMAS · 2022 to 2025
$8.0M
Task Area A shall encompass annual follow-up of cohort members, clinical events investigations, study operations, and data analysis and manuscript writing. If implemented, Task A.1 will provide fundin75N92020D00005 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WATSON, KAROL E · 2020 to 2025
$5.1M
Determinants of induced Treg and inflammatory Th17 cell balance in response to potentially pathogenic microbiotaR01AI158687 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Dan Littman · 2021 to 2026
$3.2M
Harnessing human gut-derived Bacteroides to drive systemic anti-tumor immunityK08CA283272 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Rabi Upadhyay · 2024 to 2026
$845k
Decode and design T cell induction by a complex gut microbial communityR00AI173524 · NIAID · HARVARD UNIVERSITY · PI Kazuki Nagashima · 2025 to 2026
$498k
Decode and design T cell induction by a complex gut microbial communityK99AI173524 · NIAID · STANFORD UNIVERSITY · PI NAGASHIMA, KAZUKI · 2023 to 2024
$261k
BD Canto II RUO CytometerS10RR027431 · NCRR · STANFORD UNIVERSITY · PI NOLAN, GARRY P · 2010 to 2010
$236k
Investigating a RORgt-expressing antigen presenting cell required for peripheral Treg responses to gut microbiotaF32AI181496 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Francis M Chen · 2024 to 2026
$154k
Howard Hughes Medical InstituteNCI NIH HHS K08 CA283272NCI NIH HHS P30 CA016087NCRR NIH HHS S10 RR027431NHLBI NIH HHS 75N92020D00005NIAID NIH HHS 75N93022D00005NIAID NIH HHS F32 AI181496NIAID NIH HHS K99 AI173524NIAID NIH HHS R00 AI173524NIAID NIH HHS R01 AI158687NIDA NIH HHS 75N95020D00005NIH HHS 75N93023D00005NIH HHS 75N99020D00005
6 · The paper itself

Abstract

Food antigens elicit immune tolerance through the action of intestinal regulatory T (T

Indexed as

Immune ToleranceT-Lymphocytes, RegulatoryZeinAnimalsMiceMice, Inbred C57BLZea maysZein

Identifiers

PMID41790933
PMCPMC13242657

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.