ArticleScience advances2026
A male-pheromone-elevated transcription factor ZNF362.1 in female schistosomes determines sexual maturation.
Mengjie Gu, Wenjun Cheng, Shan Li, Gongwen Chen, Xu Chen, Ruiqi Jiang, Minwei Yuan, Jing Wang, Wei Zhang, Cun Yi and 4 more
Abstract read
In one paragraphArticle in Science advances, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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2 · The registryThe trial behind it
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4 · The recordCorrections and comments
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5 · Who and what moneyAuthors and funding
14 authors.
Mengjie GuState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0000-0002-3557-6435 Wenjun ChengState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0000-0003-1867-0726 Shan LiState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Gongwen ChenState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0000-0001-5876-9902 Xu ChenState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0009-0006-5080-6581 Ruiqi JiangCollege of Life Sciences, Inner Mongolia University, Hohhot, Inner Mongolia Autonomous Region, China.
Minwei YuanCollege of Life Sciences, Inner Mongolia University, Hohhot, Inner Mongolia Autonomous Region, China.
Jing WangCollege of Life Sciences, Inner Mongolia University, Hohhot, Inner Mongolia Autonomous Region, China.
Wei ZhangState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Cun YiState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Yuxiang XieState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0009-0002-9550-8415 Xiaoling WangState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.
Wei HuState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0000-0002-4432-5400 Jipeng WangState Key Laboratory of Genetics and Development of Complex Phenotypes, Ministry of Education Key Laboratory of Contemporary Anthropology, School of Life Sciences, Fudan University, Shanghai, China.ORCID 0000-0003-0107-424X Funding
No grant is acknowledged in the PubMed record.
6 · The paper itselfAbstract
Egg production by female schistosomes drives both transmission and pathology of schistosomiasis, affecting over 200 million people. Female maturation relies on the male-derived pheromone β-alanyl-tryptamine (BATT), but underlying molecular mechanisms are unclear. We identified the BATT-responsive transcription factor gene
Indexed as
Helminth ProteinsSexual MaturationTranscription FactorsAnimalsFemaleGene Expression Regulation, DevelopmentalMaleOocytesHelminth ProteinsTranscription Factors
Identifiers
PMID41790879
PMCPMC12965309
What OpenQuestion holds
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LicenceCC BY
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