Evidence map›Paper›PMID 41790782›Full record

ArticlePLoS neglected tropical diseases2026

Evaluating how demography and temperature increase might alter the burden of congenital Toxoplasmosis in Africa.

Fidisoa T Rasambainarivo, Ingrid G Nilsson, Devin E Cheeks, Wenchang Yang, C Jessica E Metcalf

Abstract read
In one paragraph

Article in PLoS neglected tropical diseases, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Fidisoa T RasambainarivoDepartment of Biology, East Carolina University, Greenville, North Carolina, United States of America.ORCID https://orcid.org/0000-0002-7744-9477
Ingrid G NilssonDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America.
Devin E CheeksDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America.
Wenchang YangDepartment of Geosciences, Princeton University, Princeton, New Jersey, United States of America.ORCID https://orcid.org/0000-0003-0053-9527
C Jessica E MetcalfDepartment of Ecology and Evolutionary Biology, Princeton University, Princeton, New Jersey, United States of America.ORCID https://orcid.org/0000-0003-3166-7521

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of climate change on environmental pathogens is a question whose importance will amplify in coming years. The protozoan parasite and global zoonosis Toxoplasma gondii is one such: empirical evidence indicates that oocyst survival is reduced at high temperatures. Paradoxically, a decline in incidence of T. gondii infections could amplify the burden of this disease, as the most damaging outcome occurs subsequent to first infection during pregnancy, and reductions in the incidence of the infection will increase the average age of first infection. We blend models of infection dynamics rooted in occurrence across the African continent with models of human demography to bound expectations for the future burden of this pathogen, accounting for the effects of changing temperatures. We discuss targeting efforts and approaches for mitigation.

Indexed as

Toxoplasmosis, CongenitalAfricaAnimalsClimate ChangeDemographyFemaleHumansIncidencePregnancyTemperatureToxoplasma

Identifiers

PMID41790782
PMCPMC12974952

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.