Evidence map›Paper›PMID 41790624›Full record

ReviewMedicine2026

Research hotspots and trends on bee venom therapy: A bibliometric and visualization analysis from 2004 to 2024.

Kezhuo Yan, Dekai Zhou, Haipeng Lu, Zhiqing Liao, Chunyu Cai, Chenlu Hu, Wanglong Chen, Weichang Huang

Abstract readReview
In one paragraph

Review in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kezhuo YanAffiliated Guangdong Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou University of Chinese Medicine, Foshan, China.ORCID 0009-0005-1939-9714
Dekai ZhouAffiliated Guangdong Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou University of Chinese Medicine, Foshan, China.
Haipeng LuAffiliated Nanhai Hospital of Traditional Chinese Medicine, Jinan University, Foshan, China.
Zhiqing LiaoAffiliated Guangdong Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou University of Chinese Medicine, Foshan, China.
Chunyu CaiAffiliated Guangdong Hospital of Integrated Traditional Chinese and Western Medicine, Guangzhou University of Chinese Medicine, Foshan, China.
Chenlu HuAffiliated Nanhai Hospital of Traditional Chinese Medicine, Jinan University, Foshan, China.
Wanglong ChenRehabilitation Department, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, China.
Weichang HuangRehabilitation Department, Guangdong Provincial Hospital of Integrated Traditional Chinese and Western Medicine, Foshan, China.

Funding

High-Level Key Medical Specialty Development Program of Foshan City for the 14th Five-Year Plan NO. FSGSP145086Key Discipline Development Program of Traditional Chinese Medicine in Guangdong Province (Clinical) grant number [GD129] 21
6 · The paper itself

Abstract

background and purposeBee venom therapy (BVT) is widely used to treat various diseases. This study aimed to analyze the current status, research hotspots, and trends to guide future investigations.

methodsLiterature related to BVT from 2004 to 2024 was retrieved from the Web of Science core collection database. By using CiteSpace 6.2.R7 and VOSviewer 1.6.20, bibliometric and visual analyses were carried out for different categories, such as countries/regions, institutions, authors, references, and keywords.

resultsA total of 493 studies were included. This field is mainly led by Asian countries, South Korea, Kyung Hee University, and Roh Dae-Hyun, who were the most prolific country, institution, and author, respectively. "Therapeutic application of anti-arthritis, pain-releasing, and anticancer effects of bee venom and its constituent compounds" is the most co-cited reference. The analgesic mechanism of BVT, and its application in arthritis and pain management are the current research hotspots. The treatment of Parkinson disease and cancer with bee venom will become the focus of future research.

conclusionThrough bibliometric research, we investigated the overall situation in BVT over the past 2 decades, clarifying the current status, hotspots, and frontier trends in this field. To promote the advancement of BVT and overcome future bottlenecks, it is important for international institutions and research teams to strengthen collaborative exchanges and carry out high-quality, large-sample, multi-center clinical research to further explore standardized treatment protocols and mechanisms of action in BVT, driving its multidimensional development.

Indexed as

Bee VenomsBibliometricsBiomedical ResearchAnimalsHumansParkinson DiseaseBee Venomsbee venombee venom acupuncturebee venom therapyCiteSpaceVOSviewer

Identifiers

PMID41790624
PMCPMC12975270

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.