Trial reportOral and maxillofacial surgery2026
The true benefit of the regional block in orthognathic surgery lies in the preemptive effect.
Trial report in Oral and maxillofacial surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07133048 (Evaluation of Regional Blocks Efficacy in Orthognathic Surgery), which is not on this map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Evaluation of Regional Blocks Efficacy in Orthognathic Surgery
Who cites it
0 citing papers in PubMed.
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe objective of this study was to ascertain the actual benefits of regional analgesia in orthognathic surgery and to evaluate the influence of psychosocial factors on the outcomes.
methodsThis study assessed the efficacy of pre-emptive analgesic blocks in orthognathic surgery. The sample comprised 74 patients, who were randomly assigned to two groups. The first group, following the induction of general anesthesia, received maxillary and mandibular blocks with 0.5% levobupivacaine at a dosage of 5 ml per block. The second group served as the control group and received an equivalent volume of saline solution at the block injection sites. The primary hypothesis states that regional analgesia in orthognathic surgery enhances both intraoperative and postoperative analgesia. Various psychological questionnaires, pain scales, and postoperative recovery assessment tools were employed in the study.
resultsParticipants who received the analgesic block required significantly fewer postoperative analgesics compared to those in the placebo group. Additionally, participants in the experimental group reported substantially lower Visual Analogue Scale (VAS) scores than those in the control group. Participants experiencing less intense pain reported a higher quality of recovery and an improved quality of life.
conclusionsIn conclusion, the administration of pre-emptive regional nerve blocks using 0.5% levobupivacaine has been demonstrated to be effective in reducing intraoperative analgesic requirements, minimizing postoperative pain, and limiting the need for postoperative analgesics. The study was registered at www.clinicaltrials.gov (registration No. NCT07133048, Principal Investigator: David Harmicar, registration date: August 19, 2025).
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Registered trials
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