ArticlePediatric surgery international2026
Negative pressure wound therapy in children: outcomes across a heterogeneous wound cohort.
Article in Pediatric surgery international, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
purposePediatric negative pressure wound therapy (NPWT) is widely used, but etiology- and age-informed real-world benchmarks are limited. We compared treatment burden and closure trajectories across pediatric wound categories.
methodsRetrospective single-center cohort of children (< 18 years) treated with NPWT for open wounds (2020-2025). Wounds were categorized as surgical (G1), acute (G2), chronic (G3), and burns (G4). NPWT was performed in accordance with an age-adapted institutional protocol in continuous mode; dressing changes were usually performed every 72 h.
results106 patients (median age 144 months, IQR 60-180) were included: G1 42, G2 22, G3 31, G4 11. Age distribution differed by group (p < 0.001), and instillation use varied (p = 0.014). Duration was longest in G3 (median 13 [8,-24] days) and shortest in G4 (median 6 [5,-9] days), while G1 and G2 were similar. Median cycle counts were similar across groups. Re-debridement was least frequent in G1. Definitive outcomes differed by etiology: primary closure predominated in G1, secondary healing in G3, and spontaneous closure in G4; grafting occurred mainly in burns, and flap reconstruction was rare.
conclusionsNPWT was feasible across heterogeneous pediatric wounds when used with a standardized, age-adapted approach. Etiology-specific differences in burden and outcomes inform expectations and support prospective multicenter evaluation.
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