ArticleAnalytical and bioanalytical chemistry2026
Microfluidic device for electromembrane extraction with a micro-pillar stabilized liquid membrane.
Article in Analytical and bioanalytical chemistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Electromembrane extraction (EME) is a microextraction technique where charged analytes are transferred across a liquid membrane, under the influence of an electrical field, and enables selective and efficient sample cleanup. In this paper, we present for the first time a microfluidic device for electromembrane extraction where the liquid membrane was held in place by rows of micro-pillars. This design allows rapid membrane replacement, low-voltage extractions, and extended reuse, addressing key limitations of conventional EME formats. The microchip was fabricated in a stoichiometric thiol-ene polymer, offering a balance between hydrophobic and hydrophilic properties and supporting controlled flow of both aqueous and organic phases. Lidocaine was selected as the test substance for the experiments. Extraction parameters were optimized, and with a sample flow of 0.5 µL min
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