Evidence map›Paper›PMID 41790174›Full record

ArticleClinical oral investigations2026

Maintenance of physicochemical, optical, and biological properties of conventional glass ionomer cement enriched with an anacardic acid-derivative compound.

Bruna Genari, Bruna Leis Endres, Erick Rabelo, Luiz Antonio Soares Romeiro, Andressa Souza de Oliveira, Thuy Do, Reem El-Gendy, Vitória Beatriz Souza da Silva, Naile Dame-Teixeira, Fernanda Cristina Pimentel Garcia

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Article in Clinical oral investigations, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

10 authors.

Bruna GenariRestorative Dentistry Department, School of Dentistry, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Bruna Leis EndresDepartment of Dentistry, School of Health Sciences, University of Brasilia, Darcy Ribeiro University, Campus Asa Norte, Brasília, Brazil.
Erick RabeloDepartment of Dentistry, School of Health Sciences, University of Brasilia, Darcy Ribeiro University, Campus Asa Norte, Brasília, Brazil.
Luiz Antonio Soares RomeiroLaboratory for the Development of Therapeutic Innovations (LDT), Tropical Medicine Center, Faculty of Medicine, University of Brasilia, Brasilia, Brazil.
Andressa Souza de OliveiraDepartment of Pharmacy, School of Health Sciences, University of Brasilia, Brasilia, Brazil.
Thuy DoDivision of Oral Biology, School of Dentistry, University of Leeds, Leeds, UK.
Reem El-GendyDivision of Oral Biology, School of Dentistry, University of Leeds, Leeds, UK.
Vitória Beatriz Souza da SilvaDepartment of Dentistry, School of Health Sciences, University of Brasilia, Darcy Ribeiro University, Campus Asa Norte, Brasília, Brazil.
Naile Dame-TeixeiraDepartment of Dentistry, School of Health Sciences, University of Brasilia, Darcy Ribeiro University, Campus Asa Norte, Brasília, Brazil.
Fernanda Cristina Pimentel GarciaDepartment of Dentistry, School of Health Sciences, University of Brasilia, Darcy Ribeiro University, Campus Asa Norte, Brasília, Brazil. garciafcp@unb.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the physicochemical, optical, and antimicrobial properties of a conventional glass ionomer cement (GIC) modified with anacardic acid (LDT11). MATERIALS AND

methodsLDT11, extracted from cashew nutshells, was incorporated into GIC (FX ULTRA, Shofu, USA) at 0.5%, 1%, and 2% (w/w), with 0% as control. Disc-shaped specimens (6-15 mm diameter × 1 mm thickness) were prepared for all evaluations. Setting time (ISO 9917; n = 3), acid-base reaction efficiency (FTIR, COO

resultsLDT11 incorporation did not significantly affect setting time, acid-base reaction efficiency, solubility, diffusion coefficient, and surface roughness. FTIR spectra revealed no alterations in setting-related functional groups, while LDT11 was identified in the 1000-1100 cm⁻¹ range. At 2%, LDT11 significantly increased water sorption and caused visible color changes (p < 0.05). The 0.5% and 1% groups significantly reduced S. mutans viability compared to control, with the 1% group exhibiting the most pronounced and sustained effect (p < 0.0001).

conclusionsIncorporation of the anacardic acid derivative up to 1% maintained physicochemical properties of GIC while providing antimicrobial activity.

Indexed as

Anacardic AcidsGlass Ionomer CementsBiofilmsMaterials TestingSolubilitySpectroscopy, Fourier Transform InfraredStreptococcus mutansSurface Propertiesanacardic acidAnacardic AcidsGlass Ionomer CementsAnacardic acidBiofilmsBiomaterialsDental cariesGlass ionomer cementsMechanical properties

Identifiers

PMID41790174
PMCPMC12966261

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.