ArticleLangenbeck's archives of surgery2026
Differences in postoperative pain management in patients with Ileitis Crohn and diverticulitis- a matched pair analysis.
Article in Langenbeck's archives of surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeCrohn’s disease (CD) belongs to the group of chronic inflammatory bowel diseases (IBD) and is characterized by disease relapse with gastrointestinal symptoms and abdominal pain. Despite continuous development of therapeutical strategies, two thirds of patients suffering from CD need surgical intervention during their lives due to disease progression and complications. It is assumed that CD patients have increased pain experience in the perioperative setting compared to non-IBD patients, but clinical data are rare.
methodsA retrospective single-centre analysis was performed including patients with Ileitis Crohn who underwent open or minimal-invasive (laparoscopic) ileocecal resection between 2017 and 2021. The cohort was compared to patients who received open or minimal-invasive sigmoid resection due to diverticulitis. A descriptive analysis and comparison of pre-existing conditions (e.g. laboratory values, depression, preoperative (co-)analgesics use), postoperative complications, postoperative pain and pain medication was carried out in both cohorts. A matched-pair analysis was performed to determine disease-related pain levels of patients with CD in comparison to non-IBD patients. Both a previously established analgesics and a validated pain scores were used to compare the two groups.
resultsA total of 310 patients, 182 non-IBD patients and 128 CD patients, were analysed. According to Clavien Dindo classification, there were significantly more postoperative complications in CD patients (> 3a) compared to the non-IBD cohort (14.8% vs. 5.5%; p = 0.005). CD patients showed a significantly increased need for metamizole (89.1% vs. 73.1%; p < 0.001), and co-analgesics (18% vs. 4.4%; p < 0.001) postoperatively. Furthermore, the duration of intake of high-potent opioids was significantly longer compared to non-IBD patients (2.4 vs. 1.2 [days]; p = 0.038). These differences in postoperative pain management resulted in equal postoperative pain experience and sensation in patients suffering from Ileitis Crohn and diverticulitis as revealed by NRS scores. Interestingly, a matched-pair analysis between patients with limited CD and non-IBD patients (2x n = 27) showed neither significant differences in postoperative pain levels, need for additional analgesics nor the analgesic score.
conclusionsPostoperative analgesic regimen need to consider the individual patient’s pain score, pain experience and sensation irrespective of the underlying disease leading to colorectal surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.