Evidence map›Paper›PMID 41789811›Full record

Trial reportFuture oncology (London, England)2026

MISTOSUS: a phase II trial of

Katharine Offer, Marcus Reif, Clark Andersen, Jian Wang, Nancy Gordon, Karen Moody

Abstract readClinical Trial, Phase II
In one paragraph

Trial report in Future oncology (London, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Katharine OfferDepartment of Pediatrics, Joseph M. Sanzari Children's Hospital, Hackensack Meridian School of Medicine, Hackensack, NJ, USA.
Marcus ReifClinical Research, Iscador AG, Berlin, Germany.
Clark AndersenDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Jian WangDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Nancy GordonDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Children's Cancer Hospital, Houston, TX, USA.
Karen MoodyDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Children's Cancer Hospital, Houston, TX, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Relapsed resectable osteosarcoma carries a dismal prognosis of 30% 12-month post-relapse event-free survival (PREFS-12). Surgery remains the primary therapy for metastatic pulmonary osteosarcoma with the role for adjuvant therapy still undefined. There is an urgent need for effective nontoxic adjuvant therapies to improve PREFS following complete resection of metastases.

Indexed as

Antineoplastic Agents, PhytogenicBone NeoplasmsNeoplasm Recurrence, LocalOsteosarcomaPlant ExtractsViscum albumAdolescentAdultChemotherapy, AdjuvantChildFemaleHumansMalePilot ProjectsTreatment OutcomeYoung AdultAntineoplastic Agents, PhytogenicPlant ExtractsChildmistletoeosteosarcomaphase IIpulmonary relapse

Identifiers

PMID41789811
PMCPMC13048566

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.