Evidence map›Paper›PMID 41789393›Full record

ReviewTherapeutic advances in gastrointestinal endoscopy

Benign gastric outlet obstruction: evolving strategies from surgery to endoscopic ultrasound-guided gastrojejunostomy.

Giacomo Emanuele Maria Rizzo, Giuseppe Infantino, Gabriele Rancatore, Dario Quintini, Dario Ligresti, Nicoletta Belluardo, Giuseppe Rizzo, Elio D'amore, Marco Giacchetto, Ilaria Tarantino

Abstract readReview
In one paragraph

Review in Therapeutic advances in gastrointestinal endoscopy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Through-the-scope fully covered self-expandable metal stent with biflanged ends for ampullary access in severe duodenal obstruction.VideoGIE : an official video journal of the American Society for Gastrointestinal Endoscopy · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giacomo Emanuele Maria RizzoDepartment of Diagnostic and Therapeutic Services, Gastroenterology and Endoscopy Unit, Istituto Mediterraneo dei Trapianti e Terapie ad Alta Specializzazione, ISMETT-IRCCS, Palermo, Italy.ORCID https://orcid.org/0000-0001-9335-6740
Giuseppe InfantinoDepartment of Diagnostic and Therapeutic Services, Endoscopy Service, IRCCS - ISMETT, Via Tricomi 5, 90127 Palermo, Italy.ORCID https://orcid.org/0009-0004-4265-259X
Gabriele RancatoreDepartment of Diagnostic and Therapeutic Services, Gastroenterology and Endoscopy Unit, Istituto Mediterraneo dei Trapianti e Terapie ad Alta Specializzazione, ISMETT-IRCCS, Palermo, Italy.
Dario QuintiniDepartment of Diagnostic and Therapeutic Services, Gastroenterology and Endoscopy Unit, Istituto Mediterraneo dei Trapianti e Terapie ad Alta Specializzazione, ISMETT-IRCCS, Palermo, Italy.
Dario LigrestiDepartment of Diagnostic and Therapeutic Services, Gastroenterology and Endoscopy Unit, Istituto Mediterraneo dei Trapianti e Terapie ad Alta Specializzazione, ISMETT-IRCCS, Palermo, Italy.
Nicoletta BelluardoDepartment of Diagnostic and Therapeutic Services, Gastroenterology and Endoscopy Unit, Istituto Mediterraneo dei Trapianti e Terapie ad Alta Specializzazione, ISMETT-IRCCS, Palermo, Italy.
Giuseppe RizzoDepartment of Diagnostic and Therapeutic Services, Gastroenterology and Endoscopy Unit, Istituto Mediterraneo dei Trapianti e Terapie ad Alta Specializzazione, ISMETT-IRCCS, Palermo, Italy.
Elio D'amoreDepartment of Diagnostic and Therapeutic Services, Gastroenterology and Endoscopy Unit, Istituto Mediterraneo dei Trapianti e Terapie ad Alta Specializzazione, ISMETT-IRCCS, Palermo, Italy.
Marco GiacchettoDepartment of Diagnostic and Therapeutic Services, Gastroenterology and Endoscopy Unit, Istituto Mediterraneo dei Trapianti e Terapie ad Alta Specializzazione, ISMETT-IRCCS, Palermo, Italy.
Ilaria TarantinoDepartment of Diagnostic and Therapeutic Services, Gastroenterology and Endoscopy Unit, Istituto Mediterraneo dei Trapianti e Terapie ad Alta Specializzazione, ISMETT-IRCCS, Palermo, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Benign gastric outlet obstruction (bGOO) presents a significant therapeutic challenge, with etiologies ranging from peptic strictures to complex postsurgical or inflammatory conditions. While surgery has historically offered durable outcomes, its morbidity in frail populations underscores the need for effective, less invasive alternatives. This review critically examines the current literature up to April 2025 on surgical, endoscopic, and endoscopic ultrasound-guided interventions for bGOO, evaluating technical success, clinical outcomes, recurrence rates, and adverse events. Endoscopic balloon dilation shows excellent efficacy in simple peptic strictures but has limited efficacy in anatomically complex cases. Fully covered self-expandable metal stents can provide temporary relief but are associated with significant migration risk. Among emerging techniques, endoscopic ultrasound-guided gastrojejunostomy (EUS-GJ) stands out by combining the anatomical efficacy of surgery with the minimal invasiveness of endoscopy. Recent studies report technical and clinical success rates exceeding 95%, with lower recurrence and complication rates compared to traditional approaches. Comparative data increasingly support EUS-GJ as the preferred option in refractory or high-risk patients. Tailoring treatment strategies based on etiology, anatomical complexity, and patient condition is essential. EUS-GJ is redefining the therapeutic landscape of bGOO, offering a minimally invasive and durable alternative to surgery in carefully selected cases.

Indexed as

benignbGOOendoscopic ultrasoundendoscopyEUSEUS-GJgastric outlet obstructiongastroenterostomygastrojejunostomyGOO

Identifiers

PMID41789393
PMCPMC12957609

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.