ArticleAnnals of medicine and surgery (2012)2026
Roles of anesthetics in modulating neutrophil extracellular traps formation: a review of current literature.
Article in Annals of medicine and surgery (2012), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neutrophil extracellular traps (NETs) represent a critical defensive mechanism against pathogens. However, dysregulated NETs have been implicated in a range of pathological conditions. More recently, increasing attention has been given to its implications in perioperative settings. This has led to increasing interest in how common anesthetics would modulate the neutrophil ability to form NETs. Although their ability to modulate the immune system has long been recognized, a better understanding of the impact of common anesthetics on NETs release is still needed. This may reveal considerations for optimizing immune function and personalizing anesthetic techniques, especially for vulnerable perioperative and intensive care unit patients. In this review, we comprehensively discuss recent advancements in understanding the role of common anesthetics in modulating the capacity of neutrophils to form NETs and the related mechanisms. Gaining insights into the effects of anesthetics on NETs may guide new strategies to reduce complications and improve the recovery and survival of perioperative and ICU patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.