Evidence map›Paper›PMID 41789083›Full record

ReviewFrontiers in immunology2026

Health risk analysis of micro-and nanoplastic exposure via the microbiota-gut-brain axis.

Xuan Wang, Haoming Yu, Jihong Li, Shengyu Han, Yuhua Chi

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xuan WangDepartment of General Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong, China.
Haoming YuDepartment of General Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong, China.
Jihong LiDepartment of General Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong, China.
Shengyu HanDepartment of General Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong, China.
Yuhua ChiDepartment of General Medicine, Affiliated Hospital of Shandong Second Medical University, Weifang, Shandong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As global plastic pollution continues to intensify, micro- and nanoplastics have emerged as novel environmental pollutants threatening human health. These particles enter the human body through dietary ingestion, inhalation, and skin contact,accumulating within the gastrointestinal tract. Their disruption of the intestinal microbiota has become a recent research focus. Studies indicate that micro- and nanoplastics can interfere with the normal mechanisms of the microbiota-gut-brain axis via neural, immune, and endocrine pathways, thereby inducing or exacerbating diseases. This paper reviews the exposure pathways and intestinal accumulation characteristics of micro- and nanoplastics in humans, the composition of normal gut microbiota and their metabolic products, elucidates the functional pathways of the microbiota-gut-brain axis and the potential impacts of microplastics upon entering the human body, and summarises the current research status, limitations, and future prospects.

Indexed as

BrainBrain-Gut AxisEnvironmental ExposureEnvironmental PollutantsGastrointestinal MicrobiomeMicroplasticsAnimalsHumansIntestinal Barrier FunctionRisk AssessmentEnvironmental PollutantsMicroplasticsgut microbiotahealth risksintestinal barrier dysfunctionmicro- and nanoplasticsmicrobiota-gut-brain axis

Identifiers

PMID41789083
PMCPMC12957245

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.