Evidence map›Paper›PMID 41788855›Full record

ArticleJournal of nursing management2026

Self-Management Improves Long-Term CKD Prognosis: A 10-Year Retrospective Cohort Study From China.

Hui-Fen Chen, Xing-le Liang, Yan Han, Yu-Han Shen, Xian-Long Zhang, Fang Tang, Li-Zhe Fu, Yue-Yu Gu, Tao Zou, Xin-Dong Qin and 3 more

Abstract read
In one paragraph

Article in Journal of nursing management, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Hui-Fen ChenChinese Medicine Guangdong Laboratory, Department of Nephrology, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-7459-0539
Xing-le LiangChinese Medicine Guangdong Laboratory, Department of Nephrology, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0007-3685-7865
Yan HanChinese Medicine Guangdong Laboratory, Department of Nephrology, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0003-3707-4433
Yu-Han ShenChinese Medicine Guangdong Laboratory, Department of Nephrology, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0003-2863-8858
Xian-Long ZhangChinese Medicine Guangdong Laboratory, Department of Nephrology, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0002-0987-3329
Fang TangDepartment of Chronic Disease Management, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-2217-0962
Li-Zhe FuDepartment of Chronic Disease Management, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0001-9027-0386
Yue-Yu GuChinese Medicine Guangdong Laboratory, Department of Nephrology, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0003-4390-0108
Tao ZouDepartment of Chronic Disease Management, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0009-0006-9420-2210
Xin-Dong QinChinese Medicine Guangdong Laboratory, Department of Nephrology, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-9445-5326
Wen-Wei OuYangKey Unit of Methodology in Clinical Research, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, China.ORCID https://orcid.org/0000-0002-5070-6365
Xu-Sheng LiuChinese Medicine Guangdong Laboratory, Department of Nephrology, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-0931-4925
Yi-Fan WuChinese Medicine Guangdong Laboratory, Department of Nephrology, The Second Clinical College, Guangzhou University of Chinese Medicine (Guangdong Provincial Hospital of Chinese Medicine), Guangzhou, Guangdong, China.ORCID https://orcid.org/0000-0002-8498-8436

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Self-management (SMP) is a novel treatment comprised of multidimensional interventions. Researchers have reported its reliable effects on short-term improvements in surrogate indicators like 24-h urinary protein excretion and systolic blood pressure. However, whether it has any effect on long-term changes in other surrogate indicators and chronic kidney disease (CKD) endpoints remains unclear. Methods: Patients with CKD stages 3-4 were grouped into either a SMP group or a nonself-management (non-SMP) group whether they had complied any of five characterized elements: regular visits, medication adjustment, nutritional intervention, lifestyle modification, education, and behavior guide. We used 1:1 nearest-neighbor propensity score matching (PSM) to balance between-group differences. Cox regression was used to explore the long-term association between SMP and composite outcomes (all-cause mortality, end-stage kidney disease (ESKD), ≥ 50% decline in estimated glomerular filtration rate (eGFR), or doubling of serum creatinine (SCr) from baseline). Linear mixed-effects (LME) model and marginal means comparisons were used to surrogate indicators analysis. Results: The study included 1160 patients with a median follow-up of 27.20 months. Among them, 580 individuals were in the SMP group and 580 were in the non-SMP group. In the non-SMP group, the median follow-up was 24.48 (12.21, 43.39) months with 174 (30.00%) events, whereas the SMP group had a median follow-up of 29.34 (14.75, 42.00) months with 134 (23.10%) composite outcomes. Participation in a SMP program was associated with a 30.9% reduction in CKD progression risk (hazard ratio (HR) of composite outcome: 0.691, 95% CI: 0.549-0.869, and Conclusion: SMP programs are associated with a 30.9% reduction in CKD progression risk and improvements in kidney function and nutrition-related surrogate markers, benefiting CKD patients in stages 3-4.

Indexed as

Renal Insufficiency, ChronicSelf-ManagementAgedChinaCohort StudiesFemaleGlomerular Filtration RateHumansMaleMiddle AgedPrognosisProportional Hazards ModelsRetrospective Studieschronic kidney diseasedisease progressionlongitudinal dataself-management

Identifiers

PMID41788855
PMCPMC12956840

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.