Evidence map›Paper›PMID 41788813›Full record

ArticleFrontiers in pharmacology2026

Asiaticoside promotes intestinal epithelial proliferation and barrier function in ischemia/reperfusion injury by activating FoxM1.

Chenglin Zhao, Qingyu Du, Yuhang Wu, Xiangwen Zhang, Guo Zu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in pharmacology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chenglin Zhao *Department of Gastroenterology Surgery, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Qingyu Du *Department of Gastroenterology Surgery, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Yuhang Wu *Department of Gastroenterology Surgery, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Xiangwen ZhangDepartment of Gastroenterology Surgery, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.
Guo ZuDepartment of Gastroenterology Surgery, Central Hospital of Dalian University of Technology (Dalian Municipal Central Hospital), Dalian, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The most important component of intestinal ischemia/reperfusion (II/R) injury is damage to the intestinal mucosal barrier. In II/R injury, damage and restoration occur simultaneously. To develop a treatment for II/R injury, further knowledge about the restoration of intestinal barrier function is needed. Whether asiaticoside (AS) has positive effects on barrier function following II/R injury is unclear, although multiple studies have reported that AS enhances intestinal recovery after injury. In our study, we discovered that AS can reduce the intestinal Chiu score after II/R injury (

Indexed as

asiaticosidebarrier functionFoxM1intestinal ischemia/reperfusion injuryproliferation

Identifiers

PMID41788813
PMCPMC12957137

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.