ArticlePain reports2026
Sex-specific effects of naturally shorter sleep on experimental pain perception.
Article in Pain reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
3 authors.
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Abstract
Introduction: Experimental sleep loss has been linked to sex-specific alterations in pain perception, with women exhibiting greater impairment in pain inhibition. Objectives: This study investigated whether habitual short sleep (<6 hours) affects pain processing in a sex-dependent manner. Methods: A total of 81 participants (44 self-reported shorter sleepers, 37 longer sleepers) completed a night of home-based EEG sleep monitoring, followed by next-day quantitative sensory testing. A General Linear Model assessed the effects of sleep duration ( Results: A significant sleep × sex interaction ( Conclusion: Habitually short sleep is associated with impaired conditioned pain modulation in women but not in men, suggesting a sex-specific vulnerability to the effects of chronic sleep deficiency on pain regulation. These findings highlight the importance of maintaining adequate sleep duration, particularly in women, to mitigate the negative effect on pain.
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