Evidence map›Paper›PMID 41788739›Full record

ArticleCase reports in orthopedics2026

Surgical Treatment for Spinal Scoliosis in Patient With Mitochondrial Disease After Heart Transplantation: A Case Report and Literature Review.

Shintaro Abe, Masayuki Miyagi, Wataru Saito, Ryo Tamaki, Tomohisa Inoue, Kenji Hagiwara, Gen Inoue, Ken Okazaki, Masashi Takaso

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In one paragraph

Article in Case reports in orthopedics, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Shintaro AbeDepartment of Orthopaedic Surgery, School of Medicine, Kitasato University, Sagamihara, Kanagawa, Japan, kitasato-u.ac.jp.
Masayuki MiyagiDepartment of Orthopaedic Surgery, School of Medicine, Kitasato University, Sagamihara, Kanagawa, Japan, kitasato-u.ac.jp.ORCID https://orcid.org/0000-0002-3082-9739
Wataru SaitoDepartment of Orthopaedic Surgery, School of Medicine, Kitasato University, Sagamihara, Kanagawa, Japan, kitasato-u.ac.jp.
Ryo TamakiDepartment of Orthopaedic Surgery, School of Medicine, Tokyo Women's Medical University, Tokyo, Japan, twmu.ac.jp.
Tomohisa InoueDepartment of Orthopaedic Surgery, School of Medicine, Tokyo Women's Medical University, Tokyo, Japan, twmu.ac.jp.
Kenji HagiwaraDepartment of Orthopaedic Surgery, School of Medicine, Tokyo Women's Medical University, Tokyo, Japan, twmu.ac.jp.
Gen InoueDepartment of Orthopaedic Surgery, School of Medicine, Kitasato University, Sagamihara, Kanagawa, Japan, kitasato-u.ac.jp.
Ken OkazakiDepartment of Orthopaedic Surgery, School of Medicine, Tokyo Women's Medical University, Tokyo, Japan, twmu.ac.jp.
Masashi TakasoDepartment of Orthopaedic Surgery, School of Medicine, Kitasato University, Sagamihara, Kanagawa, Japan, kitasato-u.ac.jp.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We present an extremely rare case of scoliosis surgery for mitochondrial disease after heart transplantation. Case Presentation: An 18-year-old female patient with mitochondrial disease underwent heart transplantation for dilated cardiomyopathy at age 12. After heart transplantation, she presented with progressive scoliosis with a Cobb angle of 101°. Therefore, we performed spinal correction and fusion surgery under strict management. Postoperative spinal radiography revealed successful spinal correction and maintained correction 2 years after surgery. Conclusions: This is the first report of scoliosis surgery in a patient with mitochondrial disease after heart transplantation. Scoliosis surgery in patients after heart transplantation requires strict management of the circulating intravascular volume, because the denervated heart is preload-dependent. Moreover, patients with mitochondrial disease should be treated for lactic acidosis caused by surgical stress and perioperative electrolyte abnormalities. Our case showed successful performance in minimizing invasiveness without compromising the surgical goals of correction and fusion.

Indexed as

heart transplantationmitochondrial diseaseposterior spinal correction and fusion surgeryscoliosis

Identifiers

PMID41788739
PMCPMC12958027

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.