Evidence map›Paper›PMID 41788697›Full record

ArticleFrontiers in medicine2026

Linking diabetes to worsening knee osteoarthritis symptoms and disability: evidence from the osteoarthritis initiative.

Aqeel M Alenazi, Sultan A Alanazi, Abdullah M Alqthami, Mohammed K Alanazi, Bader A Alqahtani, Norah A Alhwoaimel, Ahmad D Alanazi, Sattam M Almutairi, Mohammed S Alghamdi, Yasir S Alshehri and 2 more

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Article in Frontiers in medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Aqeel M AlenaziDepartment of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia.
Sultan A AlanaziDepartment of Physical Therapy and Health Rehabilitation, College of Applied Medical Sciences, Majmaah University, Al-Majmaah, Saudi Arabia.
Abdullah M AlqthamiDepartment of Rehabilitation, King Khalid Hospital at Alkharj, Alkharj, Saudi Arabia.
Mohammed K AlanaziComprehensive Rehabilitation Center, Ministry of Human Resources and Social Development, Arar, Saudi Arabia.
Bader A AlqahtaniDepartment of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia.
Norah A AlhwoaimelDepartment of Health and Rehabilitation Sciences, College of Applied Medical Sciences, Prince Sattam Bin Abdulaziz University, Alkharj, Saudi Arabia.
Ahmad D AlanaziDepartment of Physical Therapy and Health Rehabilitation, College of Applied Medical Sciences, Majmaah University, Al-Majmaah, Saudi Arabia.
Sattam M AlmutairiDepartment of Physical Therapy, College of Applied Medical Sciences, Qassim University, Buraydah, Saudi Arabia.
Mohammed S AlghamdiDepartment of Medical Rehabilitation Sciences, College of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia.
Yasir S AlshehriDepartment of Physical Therapy, College of Medical Rehabilitation Sciences, Taibah University, Madinah, Saudi Arabia.
Vishal VennuDepartment of Rehabilitation Sciences, King Saud University, Riyadh, Saudi Arabia.
Saad M BindawasDepartment of Rehabilitation Sciences, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To examine the impact of baseline diabetes mellitus (DM) on longitudinal knee symptoms and disability in participants with knee osteoarthritis (OA). Methods: This was a secondary analysis using publicly available data from a longitudinal study design (Osteoarthritis Initiative). Data from 4,796 participants (45-79 years of age) were obtained, and only participants with grade ≥2 in either knee, using the Kellgren and Lawrence grading at baseline, were included in the current analysis. Based on self-reported DM, the participants were categorized into two groups: knee OA and DM or knee OA only. Symptoms and disability were measured using the Western Ontario and McMaster Universities Arthritis Index (WOMAC) scale and pain severity across 7- and 30-days at seven visits from baseline to 96 months of follow up. Results: A total of 2,486 participants were included and categorized into knee OA and DM ( Conclusion: This longitudinal cohort study provides evidence supporting the association between baseline DM and increased knee symptoms and disability among individuals with knee OA.

Indexed as

arthritisdiabeticsdisabilitypain intensityphysical functions

Identifiers

PMID41788697
PMCPMC12956675

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.