Evidence map›Paper›PMID 41788685›Full record

ArticleFrontiers in nutrition2026

Association of dietary flavonoid intake with incident atherosclerosis: cohort evidence in middle-aged and older adults.

Jing Tian, Sicong Wang, Xinyi Chang, Yi Han

Abstract read
In one paragraph

Article in Frontiers in nutrition, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Effects of Exogenous SA/GABA Combined with ZnSOPlants (Basel, Switzerland) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Jing TianDepartment of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Sicong WangDepartment of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Xinyi ChangDepartment of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.
Yi HanDepartment of Critical Care Medicine, The Second Affiliated Hospital of Harbin Medical University, Harbin, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: Cardiovascular disease, largely driven by atherosclerosis, remains a leading cause of global morbidity and mortality. This study aimed to investigate the associations of dietary intake of total flavonoids and their subclasses with the risk of incident atherosclerosis, post-atherosclerosis cardiovascular disease and all-cause mortality in a large prospective cohort. Methods: The study included 207,571 adults without baseline atherosclerosis from the UK Biobank. Risk factors were investigated using a three-level stepwise-adjusted Cox proportional hazards model, alongside subgroup analyses and subclass-specific analyses. Results: The prevalence of atherosclerosis showed a decreasing trend with increasing quartiles of total flavonoid intake (Q1: 0.75% vs. Q4: 0.48%, Conclusion: Higher consumption of foods rich in flavonoids-such as apples, berries, and tea-was associated with a lower risk of incident atherosclerosis. This inverse association was particularly pronounced among middle-aged and older adults aged 55 to 69. Therefore, incorporating more of these foods into daily diets may be a potential strategy to support cardiovascular health and reduce the burden of subsequent cardiovascular diseases.

Indexed as

all-cause mortalityatherosclerosiscardiovascular diseaseflavonoidmiddle-age

Identifiers

PMID41788685
PMCPMC12956777

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.