ArticleJournal of ginseng research2026
Comprehensive metabolomic profiling of
Article in Journal of ginseng research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Methods: A UPLC/Triple TOF-MS approach was employed for comprehensive characterization of the chemical constituents of PQ. Additionally, a widely targeted metabolomics approach based on UPLC/Qtrap-MS was adopted for for PQ, encompassing samples from diverse habitats ( Results: A total of 214 compounds were tentatively identified from PQ. Widely targeted metabolomics coupled with multivariate statistical analysis revealed that distinct chemical profiles existed in different habitats, different harvest seasons, and different parts of PQ. Notably, PQ samples from Shandong showed closer chemical profiles to those from North American samples. Several differential markers, including ginsenosides and organic acids, were identified and subsequently validated by precise quantification. Conclusions: This study established a comprehensive, systematic, and highly applicable qualitative and quantitative method to compare PQ from different habitats, harvesting seasons, and plant parts. The approach provided detailed chemical characterization and robust quality evaluation, offering a solid foundation for further research and application.
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