Evidence map›Paper›PMID 41788533›Full record

ArticleFrontiers in public health2026

The information challenge in public health crises: a study on the reliability and readability of information provided by large language model for thunderstorm asthma.

Zhenliang Zhu, Yanghui Feng, Feng Cao

Abstract read
In one paragraph

Article in Frontiers in public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

3 authors.

Zhenliang ZhuSchool of Nursing, Zhejiang Chinese Medical University, Hangzhou, China.
Yanghui FengDepartment of Critical Care Medicine, Zhejiang Hospital, Hangzhou, China.
Feng CaoDepartment of Critical Care Medicine, Zhejiang Hospital, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The advent of LLM (large language model) has seen extensive application in health information consultation, enabling interactive responses to complex queries; however, their reliability and readability warrant further investigation. This study aims to assess the reliability and readability of cross-disciplinary responses generated by artificial intelligence platforms regarding thunderstorm asthma, including ChatGPT-4, Deepseek-V3.2-V3.2, Perplexity Pro, and Microsoft Copilot. Methods: This study uses Google Trends to identify and filter topic-specific information on thunderstorm asthma. This study analyses cross-disciplinary responses generated by ChatGPT-4, Deepseek-V3.2, Perplexity Pro, and Microsoft Copilot in response to conversational inputs. The 29 selected responses exhibit varying levels of meteorological forecasting accuracy concerning thunderstorms, as well as prevalent themes related to asthma symptomatology and therapeutic interventions. The study employed reliability assessment tools, including the DISCERN instrument, the Ensuring Quality Information for Patients Scale (EQIP), the JAMA benchmarks, and the Global Quality Scoring (GQS), in conjunction with six authoritative readability metrics-namely, the Automated Readability Index (ARI), Coleman-Liau Grade Level (CL), Flesch-Kincaid Grade Level (FKGL), Flesch Reading Ease Score (FRES), Gunning Fog Index (GFI), and SMOG-to enable a comprehensive evaluation. Results: Research findings indicate statistically significant differences in the reliability of various artificial intelligence programmes when responding to complex interdisciplinary information queries. Microsoft Copilot demonstrates superior performance in terms of information reliability and structural quality, consistently achieving higher scores than ChatGPT-4-4o and Perplexity Pro, thereby providing more dependable information. However, all programme-generated informational responses were excessively complex for the general public, failing to meet sixth-grade reading comprehension standards, as the majority of outputs were written at a secondary education level or higher. Conclusion: This study reveals that while LLM demonstrate some reliability in handling complex health consultations, none meet the recommended readability benchmark for a sixth-grade reading level. Future efforts should focus on improving the reliability and readability of LLM generated health information to enhance comprehension amongst broader audiences.

Indexed as

AsthmaComprehensionLarge Language ModelsPublic HealthHumansReproducibility of Resultsinformation responselarge language modelreadabilityreliabilitythunderstorm asthma

Identifiers

PMID41788533
PMCPMC12957218

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.