ArticleJournal of pain research2026
Differences in Experimental Pain Sensitivity Between Non-African and African American Healthy Individuals and Patients with Painful Chronic Pancreatitis.
Article in Journal of pain research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Traditional Chinese medicine in pancreatitis: mechanisms, integrative strategies, and clinical perspectives.Frontiers in medicine · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Pancreatic Quantitative Sensory Testing (P-QST) is a neurosensory evaluation used to characterize pancreatic pain. Given racial differences in experimental pain sensitivity, it is crucial to investigate this phenomenon before widespread P-QST adoption. We aimed to study experimental pain sensitivity in African American (AA) vs non-AA individuals with no abdominal pain or known pancreatic disease (controls), and AA controls vs AA participants with chronic pancreatitis (CP). Methods: In this cross-sectional, multi-center study, race was dichotomized (AA and non-AA) and was self-reported. Participants underwent P-QST testing assessing pressure pain detection threshold (pPDT), pressure tolerance threshold (pPTT), cold pressor endurance (CPE), conditioned pain modulation (CPM), temporal summation (TS), and the Hospital Anxiety and Depression Scale (HADS). Results: A total of 157 AA and 110 non-AA control participants were tested, as well as 35 AA participants with CP. No differences in P-QST testing were seen between racial groups in control participants. Compared to AA controls, AA participants with CP showed signs of impaired CPM, significantly lower pPTTs and suggestion of lower pPDTs, as well as increased TS scores of the upper abdomen. The lower pPDTs and pPTTs and decreased CPM in AA CP participants compared to AA controls are consistent with findings in other racial groups. Conclusion: No significant differences in experimental pain results were found between AA and non-AA controls. Alterations in experimental pain sensitivity appear to mainly accompany the CP disease state in the group of AA participants studied.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.