Evidence map›Paper›PMID 41788387›Full record

ReviewLe infezioni in medicina2026

Vaginal microbiota and urinary tract infections in women: the protective role of vaginal lactobacilli in counteracting urinary tract infections occurrence and recurrence.

Francesco Moriconi, Margherita Pelagagge, Marco Bertini

Abstract readReview
In one paragraph

Review in Le infezioni in medicina, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Refractory XDRLe infezioni in medicina · 2026
    Article
  2. More than an infection: the ecological puzzle of recurrent urinary tract infections.Frontiers in cellular and infection microbiology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Francesco MoriconiMicrobiology Department of Laboratori Baldacci S.p.A., Pisa, Italy.
Margherita PelagaggePharmacovigilance Department of Laboratori Baldacci S.p.A., Pisa, Italy.
Marco BertiniR&D Department Laboratori Baldacci S.p.A of Laboratori Baldacci S.p.A., Pisa, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Urinary Tract Infections (UTIs) are common clinical conditions. Women are affected by UTIs more than men and their probability of experiencing such conditions is high (60%). The vagina and its defensive system play a key role in the pathogenesis of UTIs, making the vaginal microbiota (VMB) a target for controlling UTIs and their recurrence (rUTIs). Current therapy consists of low-dose antibiotics for rUTIs prevention. The increasing incidence of antimicrobial resistance documented to date has rendered this strategy less attractive. The initial step of UTIs pathogenesis involves colonization of the vaginal introitus and periurethra by uropathogens. The following steps may include the ascension of uropathogens via the urethra to the bladder and kidneys. Vaginal infections may be caused by uropathogens from the intestinal microbiota, taking advantage of the proximity between the anus and the vagina. Nevertheless, uropathogens may arise from the vagina itself because of alterations in VMB. Changes in VMB lead to Bacterial Vaginosis (BV), which consists of the replacement of healthy lactobacilli with unhealthy Gram-negative bacteria, such as

Indexed as

bacterial vaginosislactobacillus therapyUTIsvaginal microbiota

Identifiers

PMID41788387
PMCPMC12959630

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.