Evidence map›Paper›PMID 41788326›Full record

ReviewFrontiers in microbiology2026

Gut bacteriome alterations during high altitude exposure: a comprehensive analysis of different species.

Xinxin Yin, Jin Zeng, Zhiqi Li, Siai Chen, Changpeng Xie, Xuejing Li, Liping Zhang, Yuanming Pan, Juan An

Abstract readReview
In one paragraph

Review in Frontiers in microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xinxin Yin *Department of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Jin Zeng *Department of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Zhiqi Li *Cancer Research Center, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Siai ChenDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Changpeng XieDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Xuejing LiDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Liping ZhangDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.
Yuanming PanCancer Research Center, Beijing Chest Hospital, Capital Medical University/Beijing Tuberculosis and Thoracic Tumor Research Institute, Beijing, China.
Juan AnDepartment of Basic Medical Sciences, Qinghai University Medical College, Xining, Qinghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With the increase of high-altitude sojourn population, more and more studies on hypoxia have been conducted, but the associated changes in gut bacteriome in different hypoxic environments need to be further investigated. Gut bacteriome plays an important role in host adaptation to high-altitude hypoxia, but the contribution of gut bacteriome in high-altitude hypoxia adaptation is still controversial and may be influenced by multiple factors. In this study, we reviewed the changes in diversity and composition of the gut bacteriome of different populations of animals in different highland hypoxic environments, clarified the dynamics of the gut bacteriome during exposure to high altitude, identified the core bacteriome that may contribute to host adaptation to hypoxic environments, and comprehensively considered the effects of multiple factors on the gut bacteriome.

Indexed as

altitude hypoxiaenvironmental adaptiongut bacteriomemicrobial diversitymicrobiome

Identifiers

PMID41788326
PMCPMC12958361

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.