Evidence map›Paper›PMID 41788297›Full record

ArticleJournal of oral microbiology2026

Macrophage activation and invasion by

Aleksandra Wielento, Dominika M Drapała, Marina Terekhova, Anna Jacuła, Maxim N Artyomov, Jakub Kochan, Yoshiaki Hasegawa, Danuta Mizgalska, Juhi Bagaitkar, Aleksander M Grabiec and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of oral microbiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Pathogenicity ofFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Aleksandra WielentoDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0000-0002-3657-3164
Dominika M DrapałaDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0009-0006-1825-7172
Marina TerekhovaDepartment of Pathology and Immunology, Division of Immunobiology, Washington University School of Medicine, St. Louis, MO, United States of America.
Anna JacułaDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Maxim N ArtyomovDepartment of Pathology and Immunology, Division of Immunobiology, Washington University School of Medicine, St. Louis, MO, United States of America.
Jakub KochanDepartment of Cell Biochemistry, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.
Yoshiaki HasegawaDepartment of Microbiology, School of Dentistry, Aichi Gakuin University, Nagoya, Japan.
Danuta MizgalskaDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0000-0003-1023-9384
Juhi BagaitkarCenter for Microbial Pathogenesis, Abigail Wexner Research Institute at Nationwide Children's Hospital, Columbus, OH, United States of America.ORCID https://orcid.org/0000-0001-6185-1915
Aleksander M GrabiecDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.ORCID https://orcid.org/0000-0001-9472-850X
Jan PotempaDepartment of Microbiology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Krakow, Poland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Methods: Human monocyte-derived macrophages (MDMs) were stimulated with wild-type or mutant Results: PPAD-modified fimbriae stimulated MDM pro-inflammatory responses, such as PGE2-related gene expression and cytokine secretion, while fimbriae from accessory subunit mutants failed to induce inflammation. PPAD modification of accessory fimbrial subunits was found to protect Conclusions: These findings highlight the importance of protein citrullination in TLR2-related signaling and offer insight into how

Indexed as

accessory fimbriae subunitsfimbriaeimmune evasionmacrophagesPorphyromonas gingivalisPPADToll-like receptor 2

Identifiers

PMID41788297
PMCPMC12958381

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.