Evidence map›Paper›PMID 41788253›Full record

ReviewBiophysical reviews2025

Cholesterol in model membranes.

James H Davis

Abstract readReview
In one paragraph

Review in Biophysical reviews, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

James H DavisDepartment of Physics, University of Guelph, 50 Stone Rd. E., Guelph, N1G 2W1 ON Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cholesterol plays an important role in cell membranes through its influence on the membrane structure, stability, dynamics and phase equilibria which ultimately impact many membrane functions. Of the experimental techniques used to study the role of cholesterol in membranes, nuclear magnetic resonance is uniquely capable of providing detailed information on the molecular level as well as describing macroscopic properties such as membrane phase equilibria. This article describes three different aspects of cholesterol in model membranes: the orientation, order and dynamics of cholesterol in the lipid bilayer; the fluid-fluid two-phase coexistence found in ternary mixtures of saturated and unsaturated phosphatidylcholines with cholesterol; and the critical behaviour of these same ternary mixtures.

Indexed as

CholesterolCholesterol orientationCritical behaviourMembrane phase equilibriaMembrane rafts

Identifiers

PMID41788253
PMCPMC12957762

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.