Evidence map›Paper›PMID 41788228›Full record

ArticleInternational journal of dentistry2026

Effects of Andresen Activator on Pharyngeal Airway Volume in Growing Patients With Obstructive Sleep Apnea Syndrome: CBCT Evaluation.

Lucia Giannini, Marco Farronato, Umberto Garagiola, Gianna Dipalma, Angelo Michele Inchingolo, Francesco Inchingolo, Cinzia Maspero

Abstract read
In one paragraph

Article in International journal of dentistry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lucia GianniniFondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy, policlinico.mi.it.ORCID https://orcid.org/0000-0002-3132-1750
Marco FarronatoFondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy, policlinico.mi.it.ORCID https://orcid.org/0000-0002-6209-9873
Umberto GaragiolaDipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche, Università degli Studi di Milano, Milan, 20122, Italy, unimi.it.
Gianna DipalmaDipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche, Università degli Studi di Milano, Milan, 20122, Italy, unimi.it.ORCID https://orcid.org/0000-0002-5947-8987
Angelo Michele InchingoloDipartimento di Scienze Biomediche, Chirurgiche e Odontoiatriche, Università degli Studi di Milano, Milan, 20122, Italy, unimi.it.ORCID https://orcid.org/0000-0003-0104-6337
Francesco InchingoloDepartment of Interdisciplinary Medicine, School of Medicine, University of Bari "Aldo Moro", Bari, 70124, Italy, uniba.it.ORCID https://orcid.org/0000-0003-3797-5883
Cinzia MasperoFondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, 20122, Italy, policlinico.mi.it.ORCID https://orcid.org/0000-0002-5930-1698

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aim: To assess the effects of Andresen functional appliance therapy on the pharyngeal airway passage (PAP) in growing Class II patients presenting with obstructive sleep apnea syndrome (OSAS). This update study incorporates new data from an extended sample and a revised follow-up period to evaluate changes in airway dimensions using cone beam computed tomography (CBCT). Methods: Fifty growing patients with Class II malocclusion, mandibular hypoplasia, and OSAS, aged 9-14 (±1.63) years, were recruited for the study group. An additional 15 untreated patients (seven females and eight males) matched for age, sex, and craniofacial morphology served as the control group. Each patient had a CBCT performed before treatment (T0) and posttreatment after follow-up (16-24 months-T1). Pharyngeal airway dimensions were measured via medical 3D analysis software. The following measurements were recorded: depth of the oropharynx (DOP), depth of the hypopharynx (DHP), MP-H (linear distance from mandibular plane to hyoid), posterior nasal spine (PNS)-U (soft palate length), posterior airway space (PAS), SNA, SNB, and ANB. Statistical analysis ( Results: This study showed the effects of the Andresen appliance on Class II correction, with an increase in SNB and a reduction in ANB. PAS increased by 2.94 mm ( Conclusions: In growing Class II patients, correction of mandibular retrusion using the Andresen appliance contributes to a sagittal increase in the oropharyngeal airway. These dimensional changes in the PAP also provided clinical improvements in sleep-disordered breathing, supported by improved nocturnal polysomnographic (PSG) parameters. Such results might reduce anatomical and functional risk factors for pediatric OSAS. Functional orthopedic treatment performed during childhood has a role in airway patency promotion and long-term OSAS risk decrease. A multidisciplinary approach is advised for optimal care.

Indexed as

Andresen activatorClass IIcone beam computed tomographyfunctional applianceoropharyngeal airwayOSAS

Identifiers

PMID41788228
PMCPMC12957534

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.