Evidence map›Paper›PMID 41788214›Full record

ReviewFrontiers in plant science2026

Metabolic engineering of soybean for improving grain quality for animal consumption.

João Matheus Kafer, João Vitor da Silva, Suéllen Rosa de Almeida Polizeli, Rodrigo Thibes Hoshino, Juliana da Rosa, Elibio Leopoldo Rech Filho, Alexandre Lima Nepomuceno, Liliane Marcia Mertz-Henning

Abstract readReview
In one paragraph

Review in Frontiers in plant science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

João Matheus KaferDepartment of General Biology, Londrina State University, Londrina, PR, Brazil.
João Vitor da SilvaDepartment of General Biology, Londrina State University, Londrina, PR, Brazil.
Suéllen Rosa de Almeida PolizeliDepartment of General Biology, Londrina State University, Londrina, PR, Brazil.
Rodrigo Thibes HoshinoEmbrapa Soja, Londrina, PR, Brazil.
Juliana da RosaEmbrapa Soja, Londrina, PR, Brazil.
Elibio Leopoldo Rech FilhoEmbrapa Genetic Resources and Biotechnology, Brasilia, Distrito Federal, Brazil.
Alexandre Lima NepomucenoDepartment of General Biology, Londrina State University, Londrina, PR, Brazil.
Liliane Marcia Mertz-HenningDepartment of General Biology, Londrina State University, Londrina, PR, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Soybean is one of the main sources of vegetable protein used in animal feed, but its nutritional value is limited by the presence of antinutritional factors, such as protease inhibitors (Kunitz and Bowman-Birk), lectins, phytic acid, raffinose family oligosaccharides (RFOs), and saponins, which reduce the digestibility and absorption of nutrients. In recent decades, advances in metabolic engineering and functional genomics have allowed the targeting of biochemical pathways to increase the content and quality of proteins while simultaneously reducing these undesirable compounds. This work reviews the main progress achieved through transgenesis, induced mutagenesis, and precision gene editing, highlighting the role of tools such as RNAi, CRISPR/Cas9, and AlphaFold2-guided gene editing in modifying genes involved in carbon and nitrogen metabolism and storage proteins. Recent studies demonstrate that the silencing of negative regulatory genes, such as

Indexed as

antinutritional factorsCRISPR/Cas9protein enhancementRNA interferencesoybean biotechnology

Identifiers

PMID41788214
PMCPMC12957170

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.