Evidence map›Paper›PMID 41788193›Full record

ArticleAutism in adulthood2026

Defining Nonsuicidal Self-Injury in Autistic People: A Framework for Assessment Using Key Elements to Aid in Characterization.

Ligia Antezana, Caitlin M Conner, Jacob Feldman, Lillian L Manna, Amy Ionadi, Derica J Su, Safaa Eldeeb, Holly Gastgeb, Shalini Sivathasan, Jessie B Northrup and 3 more

Abstract read
In one paragraph

Article in Autism in adulthood, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Ligia AntezanaDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Caitlin M ConnerDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Jacob FeldmanDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Lillian L MannaDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Amy IonadiDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Derica J SuDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Safaa EldeebDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Holly GastgebDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Shalini SivathasanDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Jessie B NorthrupDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Kelly B BeckDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Lori N ScottDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Carla A MazefskyDepartment of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA.

Funding

Mental Health in Autistic Adults: An RDoC ApproachP50MH130957 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI GREG J SIEGLE · 2022 to 2026
$13.8M
CLINICAL RESEARCH TRAINING IN CHILD PSYCHIATRYT32MH018951 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI TINA R GOLDSTEIN · 1990 to 2026
$9.7M
Suicidality in autistic adults: The role of social adversity, trauma, and protective factorsR01MH139961 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Kelly Battle Beck · 2025 to 2026
$1.5M
Parent-Child Interaction and Emotion Regulation in Preschoolers with Autism Spectrum DisorderK23MH127420 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Jessie B Northrup · 2022 to 2026
$873k
NICHD NIH HHS L30 HD109969NIMH NIH HHS K23 MH127420NIMH NIH HHS L32 MH137953NIMH NIH HHS P50 MH130957NIMH NIH HHS R01 MH139961NIMH NIH HHS T32 MH018951
6 · The paper itself

Abstract

Nonsuicidal self-injury (NSSI) is the intentional destruction of one's own body tissue without suicidal intent and for purposes that are not socially or culturally accepted or practiced (e.g., intentional self-cutting, self-biting). Research on NSSI in autistic people is limited but increasing. NSSI is strongly associated with suicide, and it is an important behavior to better understand given the high rates of NSSI and suicide in autistic people. To date, research focused on autistic people has mostly used self-report questionnaires to assess NSSI, with a more limited application of clinical interviews of NSSI. However, researchers and clinicians may find it challenging to determine whether a behavior is categorized as NSSI in autistic people, especially since autistic people may present with other behaviors that cause self-injury. We set forth key elements in defining NSSI to support better reliability of NSSI assessment across studies. We emphasize that when assessing for NSSI the behavior must meet these key elements: (1) not intended to cause death, (2) the self-injury/harm is intentional, (3) there is immediate physical injury following the behavior, (4) the injury is to the external body, not internal body, (5) the injury is self-imposed and not done by another being, and (6) it is not a part of social or cultural practices. It will be important for future work to develop measures that can accurately assess NSSI in autistic people and advance mechanistic and intervention research related to NSSI.

Indexed as

emotion dysregulationnonsuicidal self-injuryNSSIrepetitive behaviorself-harmsuicide

Identifiers

PMID41788193
PMCPMC12959480

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.