ArticleSurgical case reports2026
A Rare Case of Ascending Necrotizing Mediastinitis following Perforated Appendicitis: A Case Report.
Article in Surgical case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionNecrotizing fasciitis (NF) is a rapidly progressing soft-tissue infection associated with high mortality. While descending necrotizing mediastinitis (DNM) from cervical infections is well characterized, ascending necrotizing mediastinitis (ANM) originating from intra-abdominal sources is extremely rare. CASE PRESENTATION: A 66-year-old woman presented with right flank pain, fever, and leukocytosis. CT imaging revealed a pericecal abscess and retroperitoneal air associated with perforated appendicitis. Emergency right hemicolectomy with diverting ileostomy and extensive debridement were performed. Postoperatively, the patient developed empyema and mediastinitis due to retroperitoneal infectious spread through the diaphragm. A second-look operation confirmed progressive retroperitoneal necrosis without anastomotic leakage. Given the patient's stability and prior surgical burden, mediastinitis was successfully managed with percutaneous catheter drainage (PCD). She made a full recovery following prolonged wound care and vacuum-assisted closure therapy.
conclusionsThis case highlights an exceedingly rare form of ANM originating from appendicitis. In selected patients with adequate source control and clinical stability, minimally invasive management such as PCD may be an appropriate alternative to aggressive mediastinal surgery.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.