Evidence map›Paper›PMID 41788164›Full record

ArticleBrain communications2026

Elena Gofas-Salas, Mathieu Mossad, Ysoline Beigneux, Nathaniel Norberg, Daniela Castro Farias, Catherine Vignal, Michel Paques, Céline Louapre, Kate Grieve

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04289909 (Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04289909 nacompletednot on this map

Identification of Retinal Perivascular Inflammation in Patients With Multiple Sclerosis Using Adaptive Optics

TypeinterventionalSponsorInstitut National de la Santé Et de la Recherche Médicale, FranceRan2020 to 2024Enrolled50ConditionsRelapsing Remitting Multiple Sclerosis, Progressive Multiple Sclerosis, Optic Neuritis, Eye DiseasesArmsAdaptive Optics Ophthalmoscopy (AOO)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Elena Gofas-SalasDepartment of Photonics, Sorbonne Université, CNRS, Inserm, Institut de la Vision, Paris 75012, France.ORCID https://orcid.org/0000-0003-1975-0373
Mathieu MossadDepartment of Neurology, CIC Neurosciences, Sorbonne Université, Paris Brain Institute - ICM, Assistance Publique Hôpitaux de Paris, Inserm, CNRS, Hôpital de la Pitié-Salpêtrière, Paris 75013, France.
Ysoline BeigneuxDepartment of Neurology, CIC Neurosciences, Sorbonne Université, Paris Brain Institute - ICM, Assistance Publique Hôpitaux de Paris, Inserm, CNRS, Hôpital de la Pitié-Salpêtrière, Paris 75013, France.
Nathaniel NorbergDepartment of Photonics, Sorbonne Université, CNRS, Inserm, Institut de la Vision, Paris 75012, France.
Daniela Castro FariasCHNO des Quinze-Vingts, INSERM-DGOS CIC 1423, Paris 75012, France.
Catherine VignalCHNO des Quinze-Vingts, INSERM-DGOS CIC 1423, Paris 75012, France.
Michel PaquesCHNO des Quinze-Vingts, INSERM-DGOS CIC 1423, Paris 75012, France.
Céline LouapreDepartment of Neurology, CIC Neurosciences, Sorbonne Université, Paris Brain Institute - ICM, Assistance Publique Hôpitaux de Paris, Inserm, CNRS, Hôpital de la Pitié-Salpêtrière, Paris 75013, France.ORCID https://orcid.org/0000-0002-4987-1531
Kate GrieveDepartment of Photonics, Sorbonne Université, CNRS, Inserm, Institut de la Vision, Paris 75012, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neuroinflammation plays a central role in the progression of multiple sclerosis (MS). While neuroinflammation contributes to neuronal damage, it also has regenerative roles, highlighting the complex relationship between immune responses and neurodegeneration. However, capturing the cellular processes involved in inflammation and regeneration

Indexed as

adaptive opticsinflammationmultiple sclerosisoptic neuritisretinal imaging

Identifiers

PMID41788164
PMCPMC12957951

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.