ArticleBrain communications2026
The unexpected sight: improvement of visual function following intracortical microstimulation of the human occipital cortex.
Article in Brain communications, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02983370 (Pilot Study for the Development of a Cortical Visual Neuroprosthesis for the Blind Based on Intracortical Microelectrodes), which is not on this map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Pilot Study for the Development of a Cortical Visual Neuroprosthesis for the Blind Based on Intracortical Microelectrodes
Who cites it
2 citing papers in PubMed.
- Seeing anew: Mechanisms, outcomes, and challenges in adapting to restored sight via visual prostheses.Progress in retinal and eye research · 2026Review
- Advances in neuroprostheses: interfaces, materials, and applications.Nano convergence · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We describe the case of a participant in a clinical trial investigating intracortical microstimulation of the visual cortex to provide a limited yet functional sense of vision to the profoundly blind. Prior to his formal enrolment, he was completely blind due to bilateral Non-arteritic Anterior Ischemic Optic Neuropathy. Following the initiation of brain electrical microstimulation experiments, he experienced a remarkable recovery of spontaneous vision. The regained sight, after more than 3 years of complete blindness, enabled him to perceive light and motion again and even read large characters and words, enhancing his confidence in mobility and daily activities. We conducted several behavioural and electrophysiological tests to assess and quantify his vision over time.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.