ArticleAlpha psychiatry2026
Comparison of Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) and Conventional Facemask Ventilation During Electroconvulsive Therapy in Major Mental Disorders: A Preliminary Open-Label Randomized Controlled Trial.
Article in Alpha psychiatry, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Transnasal Humidified Rapid-Insufflation Ventilatory Exchange (THRIVE) technique prolongs apnea duration. However, there is limited knowledge regarding the effectiveness and safety of THRIVE technique compared to conventional facemask ventilation during electroconvulsive therapy (ECT) in Chinese patients with major mental disorders. Methods: Seventy adult individuals with major mental disorders (schizophrenia, n = 17; bipolar disorder, n = 25; major depressive disorder, n = 28) undergoing their first ECT session were assigned to either the THRIVE group (n = 35) or the facemask group (n = 35) based on the random sequence. The primary outcome was the lowest peripheral oxygen saturation (SpO Results: In the THRIVE group, the lowest SpO Conclusions: In this preliminary open-label randomized controlled trial, the THRIVE technique appeared to be more effective than conventional facemask ventilation in preserving SpO Trial Registration: No: ChiCTR2400084318, https://www.chictr.org.cn/showproj.html?proj=229304.
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