Evidence map›Paper›PMID 41788128›Full record

ArticleCureus2026

Papillophlebitis Presenting As Optic Disc Edema Following Cervical Manipulation: A Case Report.

Hisanori Miyashita, Eri Shibuya, Hiroshi Sasaki, Eri Kubo

Abstract readCase Reports
In one paragraph

Article in Cureus, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Hisanori MiyashitaDepartment of Ophthalmology, Kanazawa Medical University, Ishikawa, JPN.
Eri ShibuyaDepartment of Ophthalmology, Kanazawa Medical University, Ishikawa, JPN.
Hiroshi SasakiDepartment of Ophthalmology, Kanazawa Medical University, Ishikawa, JPN.
Eri KuboDapartment of Ophthalmology, Kanazawa Medical University, Ishikawa, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Papillophlebitis is an uncommon inflammatory disorder of the retinal venous system that typically affects young adults but can also present in older individuals. We report the case of a 68-year-old woman who developed unilateral optic disc edema following cervical manipulation. The best-corrected visual acuity was 20/20 and 20/13 in the right and left eyes, respectively, with no relative afferent pupillary defect. Fluorescein angiography revealed disc leakage without capillary nonperfusion, and optical coherence tomography showed marked peripapillary retinal nerve fiber layer thickening without macular involvement. Brain and orbital magnetic resonance imaging revealed no abnormalities, including intracranial hypertension or venous sinus thrombosis. Based on the clinical and imaging findings, papillophlebitis was diagnosed, and oral corticosteroid therapy was initiated, resulting in the rapid resolution of disc edema and normalization of visual field findings within one month. This case highlights that a clinical picture highly suggestive of papillophlebitis can occur in older adults, potentially triggered by transient circulatory stress, and underscores the effectiveness of corticosteroid therapy in achieving complete anatomical and functional recovery of the optic nerve.

Indexed as

cervical manipulationoptic disc edemapapillophlebitisretinal venous congestionsystemic corticosteroid therapy

Identifiers

PMID41788128
PMCPMC12956486

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.