Evidence map›Paper›PMID 41787756›Full record

ArticleYeast (Chichester, England)

Candidozyma cisalpinoae sp. nov., a Genomically Distinct, Flower-Associated Yeast, Resistant to Azoles and Exhibiting Pathogenicity-Related Traits.

Anna Paula O Tironi, Katharina O Barros, Luiz Felipe A Santana, Daniela L Souza, Ana Raquel O Santos, Giovana R Ávila, Thiago M Batista, Glória R Franco, Raphael S Pimenta, Paula B Morais and 3 more

Abstract read
In one paragraph

Article in Yeast (Chichester, England). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Anna Paula O TironiDepartamento de Microbiologia, ICB, C.P. 486, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID 0009-0002-3479-1448
Katharina O BarrosDepartamento de Microbiologia, ICB, C.P. 486, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0001-9827-5966
Luiz Felipe A SantanaDepartamento de Microbiologia, ICB, C.P. 486, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Daniela L SouzaDepartamento de Bioquímica e Imunologia, ICB, C.P. 486, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID 0009-0000-9727-6713
Ana Raquel O SantosDepartamento de Microbiologia, ICB, C.P. 486, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Giovana R ÁvilaDepartamento de Microbiologia, ICB, C.P. 486, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Thiago M BatistaInstituto Nacional da Mata Atlântica, Santa Teresa, Brazil.ORCID 0000-0002-0755-1206
Glória R FrancoDepartamento de Bioquímica e Imunologia, ICB, C.P. 486, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Raphael S PimentaLaboratorio de Microbiologia Ambiental e Biotecnologia, Universidade Federal do Tocantins, Palmas, Brazil.
Paula B MoraisLaboratorio de Microbiologia Ambiental e Biotecnologia, Universidade Federal do Tocantins, Palmas, Brazil.
Marc-André LachanceDepartment of Biology, University of Western Ontario, London, Ontario, Canada.
Carlos A RosaDepartamento de Microbiologia, ICB, C.P. 486, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.ORCID 0000-0002-0056-9075
Susana JohannDepartamento de Microbiologia, ICB, C.P. 486, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico 406564/2022-1Conselho Nacional de Desenvolvimento CientÍfico e Tecnológico 0457499/2014-1Conselho Nacional de Desenvolvimento CientÍfico e Tecnológico 313088/2020-9 and 408733/2021Conselho Nacional de Desenvolvimento CientÍfico e Tecnológico 406564/2022-1Fundação Coordenação de Aperfeiçoamento de Pessoal de NÍvel Superior (CAPES)Fundação do Amparo a Pesquisa do Estado de Minas Gerais and APQ-02552-15Fundação do Amparo a Pesquisa do Estado de Minas Gerais APQ-01525-14Fundação do Amparo a Pesquisa do Estado de Minas Gerais APQ-03071-17
6 · The paper itself

Abstract

Six yeast isolates were recovered from Ipomoea flowers collected in the Cerrado biome of Tocantins, Brazil. Sequence analyses of the ITS-5.8S region and the D1/D2 domains of the large subunit (LSU) rRNA gene indicated that these isolates represent a novel species of the genus Candidozyma, phylogenetically related to Candidozyma auris and Ca. ruelliae. A phylogenomic analysis based on 2116 single-copy orthologs from Candidozyma species with available whole-genome sequences showed that the new species, represented by strain UFMG-CM-Y6065, is a sister species to Ca. ruelliae. The name Candidozyma cisalpinoae sp. nov. (MycoBank no. 861366) is proposed to accommodate the new species. The holotype is CBS16108. Sporulation or other evidence of sexual reproduction was not observed, although the genome sequence showed the presence of a functional mating type locus (MATa) and functional pheromone peptides, indicating that the species is haplontic and heterothallic. The species exhibited resistance to multiple antifungals, growth at 42°C, biofilm formation, adhesion to buccal epithelial cells, and expression of efflux pumps, traits of clinical relevance that have been reported for other species in the genus Candidozyma.

Indexed as

Antifungal AgentsAzolesDrug Resistance, FungalFlowersIpomoeaSaccharomycetalesBrazilDNA, FungalGenes, Mating Type, FungalGenome, FungalMicrobial Sensitivity TestsPhylogenyRNA, RibosomalSequence Analysis, DNAAntifungal AgentsAzolesDNA, FungalRNA, Ribosomalantifungal resistantCandidozyma cisalpinoae sp. novCerrado biomeflowerspathogenicityresistance factorsthermotolerancetropical flowersvirulence factors

Identifiers

PMID41787756
PMCPMC13067812

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.