Evidence map›Paper›PMID 41787677›Full record

ArticleThe clinical respiratory journal2026

Asthma and Infertility: A Prospective Case-Control Study on Pregnancy and Live Birth Rates in Women With Asthma Undergoing Assisted Reproduction.

Frida E Lundberg, Amalie H Sneckenborg, Hanna Nilsson, Kenny A Rodriguez-Wallberg

Abstract read
In one paragraph

Article in The clinical respiratory journal, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Frida E LundbergDepartment of Oncology-Pathology, Laboratory of Translational Fertility Preservation, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0001-7061-7178
Amalie H SneckenborgDepartment of Reproductive Medicine, Division of Gynecology and Reproduction, Karolinska University Hospital, Stockholm, Sweden.
Hanna NilssonDepartment of Oncology-Pathology, Laboratory of Translational Fertility Preservation, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0009-0009-8218-3835
Kenny A Rodriguez-WallbergDepartment of Oncology-Pathology, Laboratory of Translational Fertility Preservation, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0000-0003-4378-6181

Funding

Cancer Research Foundations of Radiumhemmet 201313Karolinska InstitutetStockholm County Council FoUI-963912Swedish Cancer Society 20 0170FSwedish Research Council 2021-06116
6 · The paper itself

Abstract

backgroundPrevious studies have suggested a negative impact of asthma on fertility, and it has been hypothesized that the underlying inflammation is playing an important role. However, available data are scarce and mostly refer to women conceiving naturally. With this study, we wished to investigate whether asthma affects the outcomes of medically assisted reproduction or not.

methodsWe conducted a prospective cohort study of 809 women, with (N = 213) or without asthma (N = 596), undergoing fertility treatment between 2009 and 2019 at one academic-based reproductive medicine center. Treatment outcome measures included clinical pregnancy rate (CPR) and live birth rate (LBR) per stimulation cycle, per oocyte pickup, and per embryo transfer, among women undergoing in vitro fertilization treatment, and LBR among women treated by intrauterine insemination. Odds ratios and 95% confidence intervals were estimated using multivariable generalized estimating equation models.

resultsNo significant differences were found in CPR or LBR between women with asthma and women without asthma undergoing in vitro fertilization (N = 694) or intrauterine insemination (N = 45). In women with asthma, the adjusted odds ratio of clinical pregnancy per embryo transfer for all cycles was 0.91 (95% CI, 0.71-1.16), and the adjusted odds ratio of live birth per embryo transfer for all cycles was 0.90 (95% CI, 0.70-1.16). The adjusted odds ratio of live birth per performed intrauterine insemination was 1.42 (95% CI, 0.63-3.21) in women with asthma.

conclusionsInfertile women with asthma undergoing medically assisted reproductive treatment have a similar chance of achieving clinical pregnancy and live childbirth when compared to infertile women without asthma.

Indexed as

AsthmaInfertility, FemaleLive BirthReproductive Techniques, AssistedAdultBirth RateCase-Control StudiesEmbryo TransferFemaleFertilization in VitroHumansPregnancyPregnancy OutcomePregnancy RateProspective Studiesassisted reproductive technologyasthmaclinical pregnancy rateinfertilitylive birth rate

Identifiers

PMID41787677
PMCPMC12963455

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.