Evidence map›Paper›PMID 41787396›Full record

SynthesisBMC public health2026

The effect of flooding on low birthweight and preterm birth: a systematic review and meta-analysis.

Antonia Mendrinos, Elly Loyd, Meredith Jagger, C Cozette Comer, Julia M Gohlke

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in BMC public health, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Antonia Mendrinos *Department of Population Health Sciences, Virginia Tech, Blacksburg, VA, 24060, USA.
Elly Loyd *Department of Population Health Sciences, Virginia Tech, Blacksburg, VA, 24060, USA.
Meredith Jagger *Independent Consultant, Austin, TX, 78746, USA.
C Cozette Comer *Evidence Synthesis Services, University Libraries, Virginia Tech, Blacksburg, VA, 24060, USA.
Julia M GohlkeDepartment of Population Health Sciences, Virginia Tech, Blacksburg, VA, 24060, USA. jgohlke@vt.edu.

Funding

NASA 80NSSC22K1048
6 · The paper itself

Abstract

backgroundNumerous studies have examined pregnancy outcomes following flood events, with the majority focusing on two related outcomes: preterm birth (PTB) and low birthweight (LBW). Summarizing the results of these previous studies and determining remaining data gaps is the main objective of this systematic review and meta-analysis.

methodsWe included publications in English that examined birthweight and/or gestational length related to exposure to floods, or events typically causing flooding (e.g. tropical cyclones). Seven academic databases were searched: CAB Abstracts (CABI), Academic Search Complete and Environment Complete (EBSCOhost), Environmental Science Index & Database (ProQuest), PubMed, Scopus, and Web of Science Core Collection. Searches were updated on February 23, 2025. For inclusion in meta-analyses, quantitative estimates of effect size and variance were required, and quality was assessed using the Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. Random effects regression was used for meta-analyses, and results are presented in forest plots, with potential for publication bias assessed in funnel plots and Egger’s test results.

resultsOverall, data from 34 studies were extracted, and 25 studies across 13 countries were included in meta-analyses. Most studies (N = 18) examined tropical cyclone exposure. Meta-analyses indicate increases in LBW (RR = 1.03, 95% CI: 1.00, 1.05) and PTB (RR = 1.10, 95% CI: 1.00, 1.22). The LBW result was not significantly influenced by quality rating, while the PTB result is non-significant when all studies, regardless of quality rating, were included in the meta-analysis (RR = 1.01, 95% CI: 0.97, 1.05). Additionally, the PTB estimate is strongly influenced by one study with a large and highly significant effect size. Additional sub-analyses suggest no decreasing effect following more recent events (after 2005).

conclusionsResults are limited by the range of methods used across studies to estimate exposure to flooding and potential co-exposures related to events that caused the flooding (e.g. wind damage-related health outcomes during tropical cyclones). Regardless, results indicate that adverse pregnancy outcomes may increase following in utero exposure to flood events. Future studies incorporating finer spatiotemporally resolved estimates of exposure to flooding will improve estimates of effect. The study is registered in PROSPERO (CRD42024514540).

Indexed as

FloodsInfant, Low Birth WeightPremature BirthFemaleHumansInfant, NewbornPregnancyDisasterFloodsLow birthweightMeta-analysisPregnancyPreterm birthSystematic reviewTropical cyclone

Identifiers

PMID41787396
PMCPMC12961868

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.