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ArticlePediatric research2026

Covid-19 pandemic in children born very premature with dysexecutive disorders: impact of isolation measures and/or neurobehavioral phenotype? A cross sectional study.

Catherine Gire, Any Beltran Anzola, Johanna Pirrello, Barthélémy Tosello, Cindy Faust, Julie Berbis

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Article in Pediatric research, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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5 · Who and what money

Authors and funding

6 authors.

Catherine GireDepartment of Neonatology, APHM, CEReSS, Health Service Research and Quality of Life Center, Nord Hospital, Aix Marseille University, Marseille, France.
Any Beltran AnzolaDepartment of Epidemiology and Health Economics, APHM, CEReSS, Health Service Research and Quality of Life Center, La Timone Hospital, Aix Marseille University, Marseille, France. any-alejandra.beltran-anzola@ap-hm.fr.ORCID http://orcid.org/0000-0003-0056-4095
Johanna PirrelloDepartment of Neonatology, North Hospital, University Hospitals of Marseille, Marseille, France.
Barthélémy ToselloDepartment of Neonatology, North Hospital, University Hospitals of Marseille, Marseille, France.
Cindy FaustDepartment of Epidemiology and Health Economics, APHM, CEReSS, Health Service Research and Quality of Life Center, La Timone Hospital, Aix Marseille University, Marseille, France.
Julie BerbisDepartment of Epidemiology and Health Economics, APHM, CEReSS, Health Service Research and Quality of Life Center, La Timone Hospital, Aix Marseille University, Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn France, following the first confinement related to the Covid-19 pandemic, strict government health guidelines aimed at limiting the spread of the disease disrupted the daily lives of children, particularly those with neurobehavioral disorders related to prematurity, which could affect their quality of life (QoL).

methodsAn observational, cross-sectional study was conducted to compare the QoL of children born very-prematurely (VP) with dysexecutive disorder, aged 7 to 9, with that of a control group of school-age children born at term of the same age, during the 6-month post-confinement period.

resultsA total of 142 children were included, 70 VP and 72 at term. There was no change in self-reported QoL in the social domains (leisure, vitality, relationships with friends and/or family) in the VP group. However, the QoL was decreased in the control group. Parents reported a negative change in the same social domains for both groups.

conclusionsSocial isolation measures during the Covid-19 had a negative impact on well-being of typically developing control-group children, whereas children born VP with specific social cognition disorders were little affected. Conditions of social isolation during Covid-19 reproduce the sociability problems experienced by children born VP due to face and emotions recognition disorders. IMPACT: School-age children born very prematurely with dysexecutive disorders considered that the social distancing measures introduced during the pandemic (Covid-19) did not impact their quality of life when they returned to school, unlike school-age children born at term. Facial and emotion recognition disorders inherent in very preterm birth were minimized by social distancing measures. Identifying an impairment risk of specific social reasoning in premature children should enable the implementation of early circumvention measures from neonatology onwards, with the aim of minimizing its impact.

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