Evidence map›Paper›PMID 41787038›Full record

ArticleAnnals of surgical oncology2026

Omitting Axillary Surgery in Patients with Ipsilateral Breast Tumor Recurrence After Breast-Conserving Surgery.

Jongyeon Yoon, Sae Byul Lee, Jisun Kim, Il Yong Chung, Hee Jeong Kim, Beom Seok Ko, Jong Won Lee, Byung Ho Son, Sei-Hyun Ahn, Do Woon Kim and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Annals of surgical oncology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jongyeon YoonDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Sae Byul LeeDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jisun KimDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Il Yong ChungDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Hee Jeong KimDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Beom Seok KoDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Jong Won LeeDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Byung Ho SonDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.
Sei-Hyun AhnDepartment of Surgery, Ewha Womans University Mokdong Hospital, Seoul, Republic of Korea.
Do Woon KimUniversity of Ulsan College of Medicine, Seoul, Republic of Korea.
Tae-Kyung Robyn YooDepartment of Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. tkyoo@amc.seoul.kr.

Funding

Asan Institute for Life Sciences, Asan Medical Center 2023IP0137
6 · The paper itself

Abstract

backgroundAxillary surgery for patients with ipsilateral breast tumor recurrence (IBTR) is feasible, but its necessity and impact on oncologic outcomes remain unclear. This study evaluated the role of axillary surgery for patients with clinically node-negative invasive IBTR.

methodsThe study identified breast cancer patients who had undergone breast-conserving surgery (BCS) at Asan Medical Center between 1990 and 2017 and later experienced invasive ipsilateral breast tumor recurrence (IBTR) as the first recurrence event. Cases with clinically node-positive disease or distant metastasis at recurrence were excluded from the analysis. Clinicopathologic features were compared using the chi-square test. Recurrence-free survival (RFS) after IBTR (second RFS) was analyzed using the Kaplan-Meier method and log-rank test in accordance with the axillary surgery status.

resultsAmong the 200 enrolled IBTR patients in the study, 60 (30%) underwent axillary surgery. The median time from primary diagnosis to recurrence was 35.5 months (range, 2-278 months), and the follow-up period after IBTR was 56.5 months (range, 1-229 months). Axillary surgery at recurrence was more frequent for patients who had not undergone axillary surgery previously and for patients undergoing salvage mastectomy. No significant difference was observed in second RFS based on whether axillary surgery was performed (5 year second RFS 61.0% with axillary surgery vs 68.4% without axillary surgery; P = 0.308). Adjuvant treatments after recurrence were similar regardless of axillary surgery.

conclusionOncologic outcomes did not differ based on whether axillary surgery was performed for IBTR patients. The omission of axillary surgery could therefore be considered in cases with clinically node-negative IBTR.

Indexed as

Breast NeoplasmsCarcinoma, Ductal, BreastLymph Node ExcisionMastectomy, SegmentalNeoplasm Recurrence, LocalAdultAgedAged, 80 and overAxillaFemaleFollow-Up StudiesHumansLymphatic MetastasisMiddle AgedPrognosisRetrospective StudiesAxillary surgeryBreast-conserving surgeryIpsilateral breast tumor recurrenceLymph node stagingOncologic outcomeRepeat surgery

Identifiers

PMID41787038

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.