Evidence map›Paper›PMID 41786931›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2026

Cochlear duct length variability in prelingual sensorineural hearing loss: Emphasis on Waardenburg syndrome and implications for cochlear implantation.

Kyu Ha Shin, Chang-Hee Kim, Yehree Kim, Jung Kyu Lee, Hye-Rim Park, Jin Hee Han, Jiyeon Yang, Bong Jik Kim, Byung Yoon Choi

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Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Kyu Ha Shin *Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea.
Chang-Hee Kim *Department of Otorhinolaryngology-Head and Neck Surgery, Konkuk University Medical Center, Research Institute of Medical Science, Konkuk University School of Medicine, Seoul, Republic of Korea.
Yehree KimDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea.
Jung Kyu LeeDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea.
Hye-Rim ParkDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea.
Jin Hee HanDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea.
Jiyeon YangDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea.
Bong Jik KimClimate-Environment-Society-Digital Innovation (CSI) Lab, Chungnam National University, Daejeon, Republic of Korea.
Byung Yoon ChoiDepartment of Otorhinolaryngology-Head and Neck Surgery, Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, 13620, Republic of Korea. choiby2010@gmail.com.ORCID http://orcid.org/0000-0001-5125-2118

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo explore the association between cochlear duct length (CDL) and hearing loss etiologies, and evaluate its impact on cochlear implantation (CI) planning.

methodsWe conducted a retrospective study on 610 patients (825 ears) who underwent CI at a tertiary center, to identify the etiologies associated with reduced CDL and investigate their influence on electrode selection and surgical outcomes.

resultsPatients diagnosed with cochlear nerve deficiency, Waardenburg syndrome (WS) associated with SOX10 variants, enlarged vestibular aqueduct syndrome, and incomplete partition type III exhibited significantly reduced CDL. Of these, WS associated with SOX10 variants exhibited the highest decrease in CDL, often with vestibular malformations.

conclusionsShort CDL poses surgical challenges, necessitating tailored electrode selection for optimal CI outcomes. In SOX10-related WS cases, preoperative imaging and genetic testing can aid in the early detection of the disease, enabling appropriate CI planning. These findings indicate the importance of having a preliminary estimation of CDL based on etiology and the significance of this study.

Indexed as

Cochlear DuctCochlear ImplantationHearing Loss, SensorineuralWaardenburg SyndromeAdolescentChildChild, PreschoolFemaleHumansInfantMaleRetrospective StudiesSOXE Transcription FactorsVestibular AqueductSOX10 protein, humanSOXE Transcription FactorsAngular insertion depthCochlear duct lengthCochlear implantEtiologyWaardenburg syndrome

Identifiers

PMID41786931
PMCPMC13152929

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.