Evidence map›Paper›PMID 41786865›Full record

ArticleScientific reports2026

Cold microwave plasma jets for wound healing: antimicrobial efficacy, mechanisms and changes in microbial cells.

Kristína Trebulová, Veronika Loupová, Barbora Chobotská, Lukáš Kletzander, Přemysl Menčík, Zdenka Kozáková, Jan Hrudka, Joanna Pawlat, Pavel Kulich, František Krčma

Erratum issuedAbstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Kristína TrebulováFaculty of Chemistry, Brno University of Technology, Purkyňova 118, 612 00, Brno, Czech Republic. xctrebulovak@vutbr.cz.
Veronika LoupováFaculty of Chemistry, Brno University of Technology, Purkyňova 118, 612 00, Brno, Czech Republic.
Barbora ChobotskáFaculty of Chemistry, Brno University of Technology, Purkyňova 118, 612 00, Brno, Czech Republic.
Lukáš KletzanderFaculty of Chemistry, Brno University of Technology, Purkyňova 118, 612 00, Brno, Czech Republic.
Přemysl MenčíkFaculty of Chemistry, Brno University of Technology, Purkyňova 118, 612 00, Brno, Czech Republic.
Zdenka KozákováFaculty of Chemistry, Brno University of Technology, Purkyňova 118, 612 00, Brno, Czech Republic.
Jan HrudkaUniversity of Chemistry and Technology Prague, Technická 5, Dejvice, 166 28, Praha 6, Czech Republic.
Joanna PawlatDepartment of Electrical Engineering and Smart Technologies, Lublin University of Technology, Nadbystrzycka Street 38A, 20-618, Lublin, Poland.
Pavel KulichVeterinary Research Institute, Hudcova 296/70, 621 00, Brno, Czech Republic.
František KrčmaFaculty of Chemistry, Brno University of Technology, Purkyňova 118, 612 00, Brno, Czech Republic.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the increasing prevalence of antibiotic-resistant microorganisms, alternative disinfection strategies are required. This study explores the antimicrobial potential of cold atmospheric plasma (CAP) as a non-thermal decontamination method for medical applications. The results confirm the efficacy of cold microwave plasma jets in the inactivation of Staphylococcus epidermidis, Escherichia coli, Cutibacterium acnes, and Nakaseomyces glabratus. Optimal treatment conditions ensuring both the antimicrobial efficacy and the safety for living tissue were established. Experiments in enclosed or open-air environment and the use of colorimetric agents confirmed that RONS, rather than UV radiation, are primarily responsible for microbial inactivation. Possible inhibition mechanisms induced by the CAP treatment were examined using scanning (SEM) and transmission (TEM) electron microscopy. The analyses revealed progressive morphological and intracellular changes in yeast cells following the plasma treatment, including localized thinning and perforation of the cell wall, vacuole enlargement, enhanced vesicle formation, protoplast aggregation and leakage of intracellular content.

Indexed as

Anti-Infective AgentsMicrowavesPlasma GasesWound HealingEscherichia coliMicroscopy, Electron, TransmissionStaphylococcus epidermidisAnti-Infective AgentsPlasma GasesElectron microscopyOxidative stress responsePlasma‑cell interactionPlasma medicineRONS mapping

Identifiers

PMID41786865
PMCPMC13079806

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.