Evidence map›Paper›PMID 41786845›Full record

ArticleScientific reports2026

A copula based supervised filter for feature selection in machine learning driven diabetes risk prediction.

Agnideep Aich, Md Monzur Murshed, Sameera Hewage, Amanda Mayeaux

Abstract read
In one paragraph

Article in Scientific reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Agnideep AichDepartment of Mathematics, University of Louisiana at Lafayette, Lafayette, LA, USA. agnideep.aich1@louisiana.edu.
Md Monzur Murshed *Department of Mathematics and Statistics, Minnesota State University, Mankato, MN, USA.
Sameera Hewage *Department of Physical Sciences and Mathematics, West Liberty University, West Liberty, WV, USA.
Amanda MayeauxDepartment of Kinesiology, University of Louisiana at Lafayette, Lafayette, LA, USA.

Funding

WV INBRE: The Inhibitor of Growth Family Member 4 (ING4) inhibits L-Type Amino Acid Transporter 1 (LAT1) expression to suppress Breast CancerP20GM103434 · NIGMS · MARSHALL UNIVERSITY · PI Travis Salisbury · 2012 to 2026
$61.1M
NIGMS NIH HHS P20 GM103434
6 · The paper itself

Abstract

Effective feature selection is critical for building robust and interpretable predictive models, particularly in medical applications where identifying risk factors in the most extreme patient strata is essential. Traditional methods often focus on average associations, potentially overlooking predictors whose importance is concentrated in the tails of the data distribution. In this study, we introduce a novel, computationally efficient supervised filter that leverages a Gumbel copula implied upper-tail concordance score ([Formula: see text], a monotone transformation of Kendall's τ) to rank features by their tendency to be simultaneously extreme with the positive class. We evaluated this method against four standard baselines (Mutual Information, mRMR, ReliefF, and L1/Elastic-Net) across four classifiers on two diabetes datasets: a large-scale public health survey (CDC, [Formula: see text]) and a classic clinical benchmark (PIMA, [Formula: see text]). Our analysis included comprehensive statistical tests, permutation importance, and robustness checks. On the CDC dataset, our method was the fastest selector and reduced the feature space by ≈52%. While this resulted in a minimal but statistically significant performance trade-off compared to using all 21 features, our filter significantly outperformed standard filters (Mutual Information, mRMR) and was statistically indistinguishable from the strong ReliefF baseline. On the PIMA dataset (8 predictors), our method's ranking produced the numerically highest ROC-AUC, despite paired DeLong tests showing no statistically significant differences versus strong baselines. PIMA thus serves as a ranking-only sanity check that our upper-tail criterion behaves sensibly in a low-dimensional clinical setting. Across both datasets, the Gumbel-[Formula: see text] selector consistently identified clinically coherent and impactful predictors. We conclude that feature selection via upper-tail dependence is an efficient and interpretable screening approach that can complement standard feature-selection baselines in public health and clinical risk prediction.

Indexed as

Diabetes MellitusMachine LearningAlgorithmsClassification AlgorithmsData AnalyticsHumansPrediction AlgorithmsPredictive Learning ModelsRisk FactorsCopula-based feature selectionDiabetesGumbel copulaMachine learningPublic healthRisk predictionSupervised feature selectionTail dependence

Identifiers

PMID41786845
PMCPMC13077058

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.