Evidence map›Paper›PMID 41786771›Full record

ArticleNPJ science of food2026

Matcha alleviates sneezing response in a murine model of allergic rhinitis.

Sawako Ogata, Naoto Uda, Kento Miura, Uyanga Enkhbaatar, Norimasa Yamasaki, Naohisa Hosomi, Akio Mori, Ryo Hasebe, Naoaki Matsuda, Fumiko Higashikawa and 6 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ science of food, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Sawako OgataDepartment of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Naoto UdaDepartment of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Kento MiuraDepartment of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Uyanga EnkhbaatarDepartment of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Norimasa YamasakiDepartment of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Naohisa HosomiDepartment of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Akio MoriDepartment of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan.
Ryo HasebeDepartment of Veterinary Pathophysiology and Animal Health, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Naoaki MatsudaDepartment of Veterinary Pathophysiology and Animal Health, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Fumiko HigashikawaMedical Center for Translational and Clinical Research, Hiroshima University, Hiroshima, Japan.
Maribet GamboaDepartment of Ecology, Faculty of Sciences, Universidad Católica de la Santísima Concepción, Concepción, Chile.
Shotaro NakajimaDepartments of Multidisciplinary Treatment of Cancer and Regional Medical Support, Fukushima Medical University School of Medicine, Fukushima, Japan.
Noriko KitamuraDepartment of Pollinosis Science, Nippon Medical School, Tokyo, Japan.
Minoru GotohDepartment of Otorhinolaryngology, Nippon Medical School, Tokyo, Japan.
Shin-Ichi SekizawaDepartment of Veterinary Pathophysiology and Animal Health, Graduate School of Agricultural and Life Sciences, The University of Tokyo, Tokyo, Japan.
Osamu KaminumaDepartment of Disease Model, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, Japan. okami@hiroshima-u.ac.jp.

Funding

Japan Society for the Promotion of Science 22H00398Japan Society for the Promotion of Science 23K07134Japan Society for the Promotion of Science 23K14117
6 · The paper itself

Abstract

Matcha, a traditional Japanese tea, has been implicated in various health effects. Herein, we investigated the impact of Matcha on allergic rhinitis by employing an allergen-induced nasal inflammation model in mice. Allergen-induced immediate nasal response, represented by the evocation of sneezing in ovalbumin-immunized mice, and subsequent nasal hyperresponsiveness, assessed by enhanced histamine-triggered sneezes, were significantly suppressed by continuous intragastric administration of hot water-extracted Matcha (250 mg/kg) with its residue. However, accumulation of inflammatory cells, total and allergen-specific IgE production, and intestinal microbiota diversity were unaffected by Matcha. Histamine- and substance P-triggered sneezes, accompanied by c-Fos expression in relevant neurons, tended to be suppressed by Matcha, whereas anti-dinitrophenyl IgE-evoked passive cutaneous anaphylaxis was unaffected. T cell receptor-stimulated CD4

Identifiers

PMID41786771
PMCPMC13022397

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.