Evidence map›Paper›PMID 41786770›Full record

Articlenpj aging2026

Cancer incidence and mortality trends among older adults.

Ryan T Morse, Kyle A Mani, Hyman B Muss, Ming Wang, Noam A VanderWalde, Grant R Williams, Nicholas G Zaorsky

Abstract read
In one paragraph

Article in npj aging, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ryan T MorseDepartment of Radiation Oncology, UNC Lineberger Comprehensive Cancer Center, University of North Carolina Hospital, Chapel Hill, NC, USA.
Kyle A ManiAlbert Einstein School of Medicine, Bronx, NY, USA.
Hyman B MussDivision of Oncology, Department of Medicine, University of North Carolina, Chapel Hill, NC, USA.
Ming WangDepartment of Population and Quantitative Health Sciences, Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Noam A VanderWaldeDepartment of Radiation Oncology, West Cancer Center and Research Institute, Memphis, TN, USA.
Grant R WilliamsDivision of Hematology/Oncology, University of Alabama Birmingham, Birmingham, AL, USA.
Nicholas G ZaorskyDepartment of Radiation Oncology, University Hospital Seidman Cancer Center, Case Western Reserve School of Medicine, Cleveland, OH, USA. nicholas.zaorsky@uhhospitals.org.

Funding

NIH T32 Geriatric Oncology Training Grant 5T32CA233419-04
6 · The paper itself

Abstract

The number of older adults with cancer in the United States is continuously growing, while disparities in cancer care remain significant. The aim of this current work is to describe epidemiological characteristics and trends in older adults with cancer. We report cancer incidence and mortality trends from 1975 and 1969, respectively, to 2019 in adults aged 65 and older abstracted from the Surveillance, Epidemiology, and End Results database in the US. Rates were used to calculate the average annual percent change (AAPC) using joinpoint regression modeling. Cancer incidence in older adults increased by an AAPC of 0.250 (P < 0.001). The greatest increases in cancer incidence were seen in melanoma of the skin (female AAPC 3.397, male AAPC 4.887); the greatest decreases in cancer incidence were in rectal (female AAPC -2.669, male AAPC -2.272) and colon cancer (female AAPC -1.734, male AAPC -1.898). Cancer mortality in older adults decreased with an AAPC of -0.317 (P < 0.001). The greatest decreases in cancer mortality were in stomach (female AAPC -2.930, male AAPC -3.013) and colon cancer (female AAPC -1.857, male AAPC -1.611); the greatest increases in mortality among females was lung cancer (AAPC 2.663), and among males was liver cancer (AAPC 1.129). Epidemiological patterns in older adults have evolved over time that differ by gender and cancer subtype.

Identifiers

PMID41786770
PMCPMC12963571

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.