Evidence map›Paper›PMID 41786735›Full record

ArticleNPJ biofilms and microbiomes2026

Dietary copper-driven colonic dysbiosis mediates oxidative stress and butyrate deficiency to facilitate the spread of resistome in pigs.

Yang Wen, Meng Gao, Zhenyu Wang, Xiaoyi Liu, Yunhui Zhang, Gang Lin, Pingli He, Hua Yang, Yingping Xiao, Wentao Lyu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in NPJ biofilms and microbiomes, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yang WenState Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China.
Meng GaoSchool of Life Sciences, Westlake University, Hangzhou, China.
Zhenyu WangState Key Laboratory of Animal Nutrition, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, China.
Xiaoyi LiuState Key Laboratory of Animal Nutrition, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, China.
Yunhui ZhangCollege of Environmental Science and Engineering, Tongji University, Shanghai, China.
Gang LinInstitute of Quality Standards and Testing Technology for Agricultural Products, Chinese Academy of Agricultural Sciences, Key Laboratory of Agrifood Safety and Quality, Ministry of Agriculture and Rural Affairs, Beijing, China.
Pingli HeState Key Laboratory of Animal Nutrition, Frontiers Science Center for Molecular Design Breeding (MOE), China Agricultural University, Beijing, China.
Hua YangState Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China. yanghua@zaas.ac.cn.
Yingping XiaoState Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China. xiaoyp@zaas.ac.cn.
Wentao LyuState Key Laboratory for the Quality and Safety of Agro-Products, Zhejiang Provincial Key Laboratory of Agricultural Microbiomics, Institute of Agro-Product Safety and Nutrition, Zhejiang Academy of Agricultural Sciences, Hangzhou, China. lvwt@zaas.ac.cn.

Funding

National Natural Science Foundation of China 32372907Natural Science Foundation of Zhejiang Province LR25C170001State Key Laboratory for Managing Biotic and Chemical Threats to the Safety of Agro-products 10417000025CE0615G
6 · The paper itself

Abstract

Copper-induced transmission of antimicrobial resistance has been well documented in livestock farming environments, but the in vivo mechanisms driving fecal resistome development remain unclear. Here, 120 mg/kg CuSO

Indexed as

BacteriaButyratesColonCopperDysbiosisOxidative StressAnimal FeedAnimalsCopper SulfateDietDietary SupplementsDrug Resistance, BacterialFecesMetagenomicsSwineButyratesCopperCopper Sulfate

Identifiers

PMID41786735
PMCPMC13084004

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.